Protein Alignment gwl and Mastl

DIOPT Version :9

• Sequence 1: NP_524860.2
• Gene: gwl / 45969
• FlyBaseID: FBgn0260399
• Length: 846
• Species: Drosophila melanogaster
• Sequence 2: XP_006254402.1
• Gene: Mastl / 307169
• RGDID: 1309186
• Length: 867
• Species: Rattus norvegicus
• Alignment Length: 922
• Identity: 321/922 - (34%)
• Similarity: 463/922 - (50%)
• Gaps: 186/922 - (20%)

  Fly    39 TTKPENHSQNAKLPTIKDFVIIKPISRGAFGKVFLGYKNNDSKRLFAIKVMRKSEMINKNMVSQV 103
            |.|..|.....:.|:|::|.|:|||||||||||:||.|.:   :|:|:||::|::||||||..||
  Rat    16 TEKCVNRIPVPRPPSIEEFTIVKPISRGAFGKVYLGQKGS---KLYAVKVVKKADMINKNMTHQV 77

  Fly   104 ITERNALALSRSQFCVSLFYSLQSLSYVYLVMEYMVGGDLKSLLAMFGYFDEPTARFYVAEMVMA 168
            ..||:|||||:|.|.|.|:|||||.|.|||:|||::|||:||||.::|||||..|..|.:|:.:|
  Rat    78 QAERDALALSKSPFVVHLYYSLQSASNVYLIMEYLIGGDVKSLLHIYGYFDEEMAIKYTSEVALA 142

  Fly   169 LQYLHQHGIVHRDIKPDNMLLSSSGHVKLTDFGLSKIDMRRDLEISDLINCSPNLN------ART 227
            |.|||:|||:|||:||||||:|:.||:|||||||||:.:.||:.:.|::. :|:::      :||
  Rat   143 LDYLHRHGIIHRDLKPDNMLISNEGHIKLTDFGLSKVTLNRDINMMDILT-TPSMSKPKQDYSRT 206

  Fly   228 PGQLLSLTSHLSF------GSEKKLNDFGSVSSGQNNGMGSVATGTSHLLQAINKHSLIMELSDS 286
            |||:|||.|.|.|      ..:...|.|.:..|......||:.
  Rat   207 PGQVLSLISSLGFFTPVGEKDQDSANVFSAPKSEAQLSQGSIC---------------------- 249

  Fly   287 EGDTSLNDAEKTS-DSKISGVSPFFSAEEANESITHTCTTNVNPQ------DSSSSCSFHTCNSA 344
              ..|::..|..| .||:  :...|....:|..|...|.|:...|      .||:|...||..|:
  Rat   250 --PMSIDQKEPVSYSSKL--LKSCFETLASNPEIPVKCLTSNLLQCRKRLGTSSTSSQSHTFVSS 310

  Fly   345 DLSKC-SPPLESKDGAAAG-------------------NAIPSKRRVEFVLDAAPCQGCKLAEQD 389
            ..|:| |.|...||..:|.                   :||.:|..:|..|...         .|
  Rat   311 VESECHSSPKWEKDCQSAKPSSTMMSWSAGEMPYAKSVSAIETKTDLELALSPI---------HD 366

  Fly   390 SSNMATNDGKH--LPKIDNAIEASFEFSMVRRRSVDERNRISKGPEDSGVSSRKGDDYSSC---H 449
            |||:......:  ||:...:.|.|:|     .|..|..|           .:...|:.|.|   |
  Rat   367 SSNIPPTGRNYMTLPRKCFSREISWE-----AREPDINN-----------ETMTIDEVSFCQSNH 415

  Fly   450 LNLNSESTAS------SIEKN---VDN-----LSQSKEDFSCSDYSRSYNVTN--GNEMSGINMN 498
            ..:||.:|:.      :.::|   ||:     :.|||:  :|.:|..:...|.  .|:.:|  :.
  Rat   416 WAVNSSATSEEHLCKRNCKRNFHLVDSSPCQEIIQSKK--NCIEYEANKEKTGCCANQATG--LT 476

  Fly   499 SPFRNLSKHF---KRPDFL-----------RGMKRKINLVNRSDN-MSSMDTD-------GCSSS 541
            :..:||....   ::.|:.           |....::::...:.| ||.:|.|       .|..|
  Rat   477 AQVQNLKLSVCKSQQHDYANKENTVTYLTDRRTPEELHIPTIAKNLMSELDEDCELSSKKDCLHS 541

  Fly   542 NG-STNTGLTQEIEILNIGSSTPKKRKARSSPIRGVLKVRSLSDDEMPINHLLGPEANVANVVFS 605
            |. .::.....:...::..||.|......||     |::::|..|: .|......|.|..:::..
  Rat   542 NSVCSDEDRAPKTVCVDSDSSFPGVSMMESS-----LEIQALEPDK-SIRDYSFEEPNTEDLLML 600

  Fly   606 TPVSSQKLPRRDGGLLGKLKATRFALPLSIENKKREHATADKMSGIQY-----HLKLSDDPTMSP 665
            .......||:.|.....:......|.|     .|.....|.|.:.:.:     |:..|.:...|.
  Rat   601 PKCQENSLPKDDWHASIQDSNQMLAPP-----SKAPKTFASKTNVVAFRSFSSHINASSNSEPSK 660

  Fly   666 IN-----------HGAGNLP----------------KTPKNVNINTPFRTPKSVRRG-ARVSNER 702
            ::           ..:|:.|                :||..|.:.|.:||||||||| ..|.:.|
  Rat   661 VSTTSLDTMDISCDYSGSCPMAVTPTEKGRACVSHQQTPSQVKLGTSYRTPKSVRRGPPPVDDGR 725

  Fly   703 ILGTPDYLAPELLLKQGHGPAVDWWALGVCFYEFMTGIPPFNDETPQKVFDNILNKNIEWPEGDE 767
            ||||||||||||||...|||||||||||||.:||:||||||||||||:||.|||.::|.||||:|
  Rat   726 ILGTPDYLAPELLLGAAHGPAVDWWALGVCLFEFLTGIPPFNDETPQQVFQNILKRDIPWPEGEE 790

  Fly   768 ALSVESMEAVELLLTMDPNERPAAKEVQQMRHFACIDWENIGNTEPPFVPTPDNPTDTGYFDARN 832
            .||.:|..|:::|||:|..:|...||::....|:.:||||:.:...||||.|||.|||.||:|||
  Rat   791 KLSDKSQSAMDMLLTIDDTKRAGMKELKHHPLFSEVDWENLQHQTMPFVPQPDNETDTSYFEARN 855

  Fly   833 NLQHLQLSNFAL 844
            |.|||.:|.|:|
  Rat   856 NAQHLTISGFSL 867

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gwl	NP_524860.2	STKc_MASTL	52..>255	CDD:270761	115/214 (54%)
		S_TKc	57..>205	CDD:214567	95/147 (65%)
		PKc_like	<655..835	CDD:304357	103/207 (50%)
Mastl	XP_006254402.1	STKc_MASTL	29..>222	CDD:270761	113/196 (58%)
		S_TKc	34..>194	CDD:214567	99/163 (61%)
		PKc_like	<659..858	CDD:304357	102/198 (52%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	201	1.000	Domainoid score	I2929
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	458	1.000	Inparanoid score	I1521
OMA	1	1.010	-	-		QHG47788
OrthoDB	1	1.010	-	-		D376375at33208
OrthoFinder	1	1.000	-	-		FOG0007311
OrthoInspector	1	1.000	-	-		oto98077
orthoMCL	1	0.900	-	-		OOG6_107501
Panther	1	1.100	-	-	LDO	PTHR24356
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1837
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	10.070