Protein Alignment gwl and Mast2

DIOPT Version :9

• Sequence 1: NP_524860.2
• Gene: gwl / 45969
• FlyBaseID: FBgn0260399
• Length: 846
• Species: Drosophila melanogaster
• Sequence 2: NP_001355990.1
• Gene: Mast2 / 17776
• MGIID: 894676
• Length: 1801
• Species: Mus musculus
• Alignment Length: 790
• Identity: 140/790 - (17%)
• Similarity: 211/790 - (26%)
• Gaps: 476/790 - (60%)

  Fly    50 KLPTIKDFVIIKPISRGAFGKVFLGYKNNDSKRLFAIKVMRKSEMINKNMVSQVITERNALALSR 114
            |.|:.:||..||.||.||:|.||| .::..:::.||:|.:.|..:|.:|.:.|...||:.|..:.
Mouse   513 KTPSEEDFETIKLISNGAYGAVFL-VRHKSTRQRFAMKKINKQNLILRNQIQQAFVERDILTFAE 576

  Fly   115 SQFCVSLFYSLQSLSYVYLVMEYMVGGDLKSLLAMFGYFDEPTARFYVAEMVMALQYLHQHGIVH 179
            :.|.||:|.|.::..::.:||||:.|||..:||...|.......|.|.||.|:||:|||.:||||
Mouse   577 NPFVVSMFCSFETKRHLCMVMEYVEGGDCATLLKNIGALPVDMVRLYFAETVLALEYLHNYGIVH 641

  Fly   180 RDIKPDNMLLSSSGHVKLTDFGLSKIDMRRDLEISDLINCSPNLNARTPGQLLSLTSHLSFGSEK 244
            ||:||||:|::|.||:||||||||||.                        |:|||::|..|
Mouse   642 RDLKPDNLLITSMGHIKLTDFGLSKIG------------------------LMSLTTNLYEG--- 679

  Fly   245 KLNDFGSVSSGQNNGMGSVATGTSHLLQAINKHSLIMELSDSEGDTSLNDAEKTSDSKISGVSPF 309
                                                                             
Mouse   680 ----------------------------------------------------------------- 679

  Fly   310 FSAEEANESITHTCTTNVNPQDSSSSCSFHTCNSADLSKCSPPLESKDGAAAGNAIPSKRRVEFV 374
                                                                             
Mouse   680 ----------------------------------------------------------------- 679

  Fly   375 LDAAPCQGCKLAEQDSSNMATNDGKHLPKIDNAIEASFEFSMVRRRSVDERNRISKGPEDSGVSS 439
                                     |:.|                   |.|
Mouse   680 -------------------------HIEK-------------------DAR-------------- 686

  Fly   440 RKGDDYSSCHLNLNSESTASSIEKNVDNLSQSKEDFSCSDYSRSYNVTNGNEMSGINMNSPFRNL 504
                                                                             
Mouse   687 ----------------------------------------------------------------- 686

  Fly   505 SKHFKRPDFLRGMKRKINLVNRSDNMSSMDTDGCSSSNGSTNTGLTQEIEILNIGSSTPKKRKAR 569
                   :||
Mouse   687 -------EFL------------------------------------------------------- 689

  Fly   570 SSPIRGVLKVRSLSDDEMPINHLLGPEANVANVVFSTPVSSQKLPRRDGGLLGKLKATRFALPLS 634
                                                                             
Mouse   690 ----------------------------------------------------------------- 689

  Fly   635 IENKKREHATADKMSGIQYHLKLSDDPTMSPINHGAGNLPKTPKNVNINTPFRTPKSVRRGARVS 699
                                                                             
Mouse   690 ----------------------------------------------------------------- 689

  Fly   700 NERILGTPDYLAPELLLKQGHGPAVDWWALGVCFYEFMTGIPPFNDETPQKVFDNILNKNIEWPE 764
            ::::.|||:|:|||::|:||:|..|||||:|:..|||:.|..||..:||:::|..:::..|.|||
Mouse   690 DKQVCGTPEYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDEIVWPE 754

  Fly   765 GDEALSVESMEAVELLLTMDPNER---PAAKEVQQMRHFACIDWENIGNTEPPFVPTPDNPTDTG 826
            ||:||..::.:....||..:|.||   .:|.||:|...|..:||..:...:..|:|..::..||.
Mouse   755 GDDALPPDAQDLTSKLLHQNPLERLGTSSAYEVKQHPFFMGLDWTGLLRQKAEFIPQLESEDDTS 819

  Fly   827 YFDARNNLQH 836
            |||.|:...|
Mouse   820 YFDTRSERYH 829

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gwl	NP_524860.2	STKc_MASTL	52..>255	CDD:270761	78/202 (39%)
		S_TKc	57..>205	CDD:214567	68/147 (46%)
		PKc_like	<655..835	CDD:304357	54/182 (30%)
Mast2	NP_001355990.1	DUF1908	202..483	CDD:312475
		STKc_MAST	519..798	CDD:270760	127/751 (17%)
		PDZ_signaling	1110..1191	CDD:238492

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0606
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900