Protein Alignment Pep and Pep

DIOPT Version :10

• Sequence 1: NP_524858.1
• Gene: Pep / 45961
• FlyBaseID: FBgn0004401
• Length: 716
• Species: Drosophila melanogaster
• Sequence 2: XP_061500341.1
• Gene: Pep / 1275094
• VectorBaseID: AGAMI1_002413
• Length: 692
• Species: Anopheles gambiae
• Alignment Length: 776
• Identity: 292/776 - (37%)
• Similarity: 390/776 - (50%)
• Gaps: 176/776 - (22%)

  Fly    24 MAFRGNQNRNRNFGGGNNNYGGPMGANRMGGMNMSPWESQNPGGG---QFGNNMRQ--------- 76
            ||:|.|.|| |..|||:...||..|....||           |||   .||||...
Mosquito     1 MAYRNNNNR-RGGGGGSGGGGGGSGGGGGGG-----------GGGSSSNFGNNYGNRINPWDAGV 53

  Fly    77 GGGQMNAQAINLANNLLNNLFRNQNP----PSLLDLPRGGGGMGNRNQRGGPMVSRGGGAGNRLN 137
            ||.::|..|::.||:|:|||..|||.    |||||        |.::.|...|     ...|.:.
Mosquito    54 GGVRVNNDALSFANSLINNLLGNQNANHQVPSLLD--------GVQSSRFDDM-----NGYNFIR 105

  Fly   138 NRRGQGGGFQNRGATGSGPKPPPKQGGGGIRKQNAFDRAKKLLAKNANQNKKKE----------- 191
            ||.     .:||...|.           ||||.:|..|:|.:|:||.|:...|:
Mosquito   106 NRY-----TKNRNINGR-----------GIRKPDAVVRSKNVLSKNYNKPLGKDALGNAGTSSRN 154

  Fly   192 ----------------PTPGEKKIESPTKESPYASVPNDMFYCHLCKKHMWDANSFENHIKGRTH 240
                            |..|.|:..|.:|.|||..|.||..|||:|.|||:||.||||||.||||
Mosquito   155 DHSGNKGVKKGNPAGGPVGGSKEKSSTSKVSPYMDVSNDFLYCHMCDKHMYDATSFENHITGRTH 219

  Fly   241 LMMREGIEESYRLKANMIRQEAKIAEQLKSIEFDRLKRMGKSKQ--RQLDYCTMCDLNFHGHIST 303
            .:|:|.||||||::|.::||||:||||||:||.||||||||:|.  :..:||.||:|.|:|||..
Mosquito   220 RVMKESIEESYRMRATLLRQEARIAEQLKTIEIDRLKRMGKAKNYYKVREYCPMCELFFYGHIIA 284

  Fly   304 HRKSEGHLQLKKFLHPKCIECNKEFATRIDYDTHLLSAEHLKKAAENNTKVG-ERKRQTLPISTE 367
            ||:||.||.|||||||||.:|..||..|.:||.||||..|:|......:::. |||.:.|.|||.
Mosquito   285 HRRSEKHLDLKKFLHPKCDDCELEFHNRTEYDDHLLSVVHMKNCKSKPSRLEIERKAKQLTISTM 349

  Fly   368 EEETRDLR---LPQKRKKKPVK----KEGEAADGEAKKEGAGDGEGAEGDEAEGEEAKEGEE--- 422
            .:|..|:|   .|:|||:|...    |:.:.....|.|....:...:.|.|..||.:|.|||
Mosquito   350 NDELLDIREEIAPKKRKEKDTSGTSTKKSDIEGKSATKTQLAEQSASGGTEENGESSKVGEEGTA 414

  Fly   423 ----AADE---------------TKEGDELNESQEEEEVALPVDPEDCILDFNDGDEIPSEVDTR 468
                .||:               |.:..:|:|...|:|:....:.||||||:..||||..|:|.:
Mosquito   415 MAEATADDAGDCSKPSVEDGVGATLDDPKLDEECPEDEMVKEEESEDCILDYKPGDEIAPEIDNK 479

  Fly   469 LPKYNWQRAVGPGLISKLECYECSVCSKFFDTEVTAEIHSRTATHHRNFLKFINEKSSDTKIAQK 533
            ||:|...||:|..||.||||.||.:|.|:||:|.|.|:|:||.:|:|.|::|:|||:.:.:||||
Mosquito   480 LPRYKKNRALGLSLIGKLECVECRICHKYFDSEATGEVHARTHSHYRAFIRFLNEKAMEVRIAQK 544

  Fly   534 RAAAALEENE--RKKRKVEEAEAPAAEGAAEETTEGAEGE-----LYDPSEATGDDEDVEMVDDN 591
            ||..||||.|  :||:|:.:.:....|...|:...| |||     ||||||||
Mosquito   545 RAVVALEEAEAAKKKQKLVDEKKCTGEQNGEQANNG-EGEKKDSDLYDPSEAT------------ 596

  Fly   592 AEGEGEGEGDEEAEAEVEEDGAGQD--NGEEEMEAQEEEGQEGEQEPEPEPAPVQTPAPAEPAPP 654
                      |..:|.:.|||...|  ||.|::|                  |::|.|.::..
Mosquito   597 ----------ESGDASMAEDGKSDDGHNGSEQVE------------------PMETEAASDLV-- 631

  Fly   655 AKTPAKTPTKAAAPAAVASPAAAATSADASPSPAKKATPARAAAGAKATPQRQRARGRYNR 715
            .|..|:|.|   .||.....:.|.|.||:|     |...::.:...|..|:....|||..|
Mosquito   632 GKDGARTST---TPANEDDESGAQTEADSS-----KEDDSKESKDDKPNPKGGNRRGRNTR 684

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pep	NP_524858.1	zf-C2H2_jaz	216..240	CDD:432381	17/23 (74%)
		C2H2 Zn finger	290..310	CDD:275371	12/19 (63%)
		C2H2 Zn finger	321..343	CDD:275371	11/21 (52%)
Pep	XP_061500341.1	None