Protein Alignment aly and mip130

DIOPT Version :9

• Sequence 1: NP_001261348.1
• Gene: aly / 45960
• FlyBaseID: FBgn0004372
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: NP_569958.2
• Gene: mip130 / 31153
• FlyBaseID: FBgn0023509
• Length: 986
• Species: Drosophila melanogaster
• Alignment Length: 609
• Identity: 132/609 - (21%)
• Similarity: 237/609 - (38%)
• Gaps: 173/609 - (28%)

  Fly    66 IRISEKPEIQGRIKPGVASK----------------RTENFTKKPSNISVDVSEDEKAKEKEKEQ 114
            :..|.:|::.|:.|....||                |..:|..|.:..:|......:.:..:.|.
  Fly   213 VSASNQPQLLGKHKKATPSKSQSVGSKLGSGGPKTGRGAHFIGKGTAAAVAAVAAAEEEANQAEA 277

  Fly   115 DPYSNDFI---LGKRLYNFLKYLSSHRWIWCEFVDSFLDKPTLTMGYDMKRFIAEYCPLLHSCFM 176
            ...:|..:   :|.||.|.||...:|:|...|:..|::|||......:....:.|..|.|.:..:
  Fly   278 AALANKRLGQSIGLRLRNLLKLPKAHKWAIAEWFYSYVDKPLFECRDEFMNHVNELAPRLGTRSL 342

  Fly   177 PRRGWQLVRRNMGKARRFSAAFIELEREELECQRRIVRQLQQHKFNP---KENVGYLDQIPKRVP 238
            .|..|..:||.||:.||.||.|...||:||:.:|:::|.||..|  |   |::|..|..:|:::|
  Fly   343 IRHEWVNIRRRMGRPRRCSAKFFSEERKELDRKRQVIRTLQSRK--PGEFKDSVSMLSDMPEKIP 405

  Fly   239 LPLAKDATVSSFLHGNSFEGIVNGTVMGYDPQDYTYLVRFNRNDNAVVL---SLPDSQLYSDEET 300
            :.|.....|::.|.... :||..|||..||..:..|.|.|.|    :.|   ::||.::.|:...
  Fly   406 MTLPLGTKVTARLRSPQ-DGIFAGTVAAYDSLNAMYRVTFER----IGLGTHAIPDYEIVSENFH 465

  Fly   301 AAVPL------------------------------------------------------------ 305
            ..:||
  Fly   466 EMLPLHSFTKDFRPNLMSIYQTNNLGFTTNLGFTANLTNNYLQKKEKIDGGAGAAAGAGSLYFKP 530

  Fly   306 -------------SIIMRGNKSSSVISESA------KTEKFGNKRYTKELLESVLRVGKLQDVKH 351
                         ::.|:.|||..::.:.:      :.:...|:.|:..|||.::|:.|...||.
  Fly   531 QKHLATNNAAARNALSMKLNKSDPLLGQDSVGVSPIRQQLTRNRGYSTSLLEHLVRLEKYIAVKA 595

  Fly   352 KILMDLARMN-------EDFETFKEIGSSSSRRDAKVTPQRENLQRRYSASMITLHRVNADILEP 409
            ..:..|.:||       .|..:..|.|....|:.|      .|.||:|:.:::|:.|:||::
  Fly   596 DRIQRLNKMNGTAELAMGDMISHDENGDRHRRQIA------VNFQRQYAFNIVTIERINAEL--- 651

  Fly   410 LRILHDYLVEYQKQDEEEESKRGRP-----ASEVY--QKCRMQAEQDLKTAADEKFLKIESDRTQ 467
                   :.|..|..|...|....|     .|..|  ::||.:|.|   |..|.....:::.|..
  Fly   652 -------MFELTKVQELSSSLTRNPNVQAMISPTYLREECRAKASQ---TVDDINKGMVKNTRMI 706

  Fly   468 EFVRNLHTILYLNGKLG-----RENSSNLETIIADLVTHMV----------------DNIQPSLG 511
            :.:::|.|:|.:...||     .|.:..||..:.::.::::                :.|...:.
  Fly   707 KLLKDLTTLLIVTQNLGGDCEVSEVNEVLEGCLEEVRSNLICSENREVFQMSVQGRLEYIAMDIS 771

  Fly   512 RKLK--------DGVDSLEPLRQQ 527
            |:|:        ||.|.::.|:.:
  Fly   772 RRLEEKSLSRVADGDDDIKSLKSE 795

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
aly	NP_001261348.1	DIRP	147..252	CDD:284095	35/107 (33%)
mip130	NP_569958.2	DIRP	311..419	CDD:284095	35/109 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45438637
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1019
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	84	1.000	Inparanoid score	I3747
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005813
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR21689
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.890