DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mts and PPT1

DIOPT Version :9

Sequence 1:	NP_001285724.1	Gene:	mts / 45959	FlyBaseID:	FBgn0004177	Length:	309	Species:	Drosophila melanogaster
Sequence 2:	NP_011639.3	Gene:	PPT1 / 853023	SGDID:	S000003355	Length:	513	Species:	Saccharomyces cerevisiae

Alignment Length:	265	Identity:	98/265 - (36%)
Similarity:	147/265 - (55%)	Gaps:	11/265 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 LTETQVRTLCDKAKEILSKESNVQEVK------CPVTVCGDVHGQFHDLMELFRIGGK-SPDTNY 80
            |.:..|..:...|..:..:|.::.|::      ..::||||.||||:|::.|||..|| .|...|
Yeast   209 LPKKYVAAIISHADTLFRQEPSMVELENNSTPDVKISVCGDTHGQFYDVLNLFRKFGKVGPKHTY 273

  Fly    81 LFMGDYVDRGYYSVETVTLLVALKVRYRERITILRGNHESRQITQVYGFYDECLRKYGNANVWKY 145
            ||.||:||||.:|.|...|...||:.:.....:.||||||..:.::|||.|||..|| :..::..
Yeast   274 LFNGDFVDRGSWSCEVALLFYCLKILHPNNFFLNRGNHESDNMNKIYGFEDECKYKY-SQRIFNM 337

  Fly   146 FTDLFDYLPLTALVDGQIFCLHGGL--SPSIDSLDHIRALDRLQEVPHEGPMCDLLWSDPDDRGG 208
            |...|:.|||..|::.....:||||  .||. :|...:.:||..:.|.:|...:|||:||.:..|
Yeast   338 FAQSFESLPLATLINNDYLVMHGGLPSDPSA-TLSDFKNIDRFAQPPRDGAFMELLWADPQEANG 401

  Fly   209 WGISPRGAGYTFGQDISETFNNTNGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQA 273
            .|.|.||.|:.||.||::.|...|.|..:.|:|:|.|.|..:.....::|:|||||||...||..
Yeast   402 MGPSQRGLGHAFGPDITDRFLRNNKLRKIFRSHELRMGGVQFEQKGKLMTVFSAPNYCDSQGNLG 466

  Fly   274 ALMEL 278
            .::.:
Yeast   467 GVIHV 471

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mts	NP_001285724.1	MPP_PP2A_PP4_PP6	9..293	CDD:277360	98/265 (37%)
PPT1	NP_011639.3	PLN03088	10..>130	CDD:215568
		TPR repeat	12..40	CDD:276809
		TPR repeat	45..75	CDD:276809
		TPR repeat	80..108	CDD:276809
		MPP_PP5_C	165..508	CDD:277362	98/265 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0639
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810