Protein Alignment mts and PPP6C

DIOPT Version :10

• Sequence 1: NP_476805.1
• Gene: mts / 45959
• FlyBaseID: FBgn0004177
• Length: 309
• Species: Drosophila melanogaster
• Sequence 2: NP_001116827.1
• Gene: PPP6C / 5537
• HGNCID: 9323
• Length: 342
• Species: Homo sapiens
• Alignment Length: 350
• Identity: 173/350 - (49%)
• Similarity: 216/350 - (61%)
• Gaps: 61/350 - (17%)

  Fly     9 DLDQWIEQLNECNQLTETQVRT-------------------------------------LCDKAK 36
            |||:::|....|..|.|..::.                                     |||...
Human     5 DLDKYVEIARLCKYLPENDLKVSPICGLAPSGCGAPAGRPFLSPGPPPVFHFLRFLKERLCDYVC 69

  Fly    37 EILSKESNVQEVKCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLV 101
            ::|.:|||||.|..|||||||:||||:||.||||.||:.|||||:||||:|||||||:||.|.|:
Human    70 DLLLEESNVQPVSTPVTVCGDIHGQFYDLCELFRTGGQVPDTNYIFMGDFVDRGYYSLETFTYLL 134

  Fly   102 ALKVRYRERITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCL 166
            |||.::.:|||:||||||||||||||||||||..||||||.|:|.|.:||.|.:.||:|.||.|:
Human   135 ALKAKWPDRITLLRGNHESRQITQVYGFYDECQTKYGNANAWRYCTKVFDMLTVAALIDEQILCV 199

  Fly   167 HGGLSPSIDSLDHIRALDRLQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNNT 231
            ||||||.|.:||.||.::|.||:||:|..|||:||||:|...|.|||||||:.||..::..|.:.
Human   200 HGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSDPEDVDTWAISPRGAGWLFGAKVTNEFVHI 264

  Fly   232 NGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAALMELDDSLKFSFLQFDPAPRRG 296
            |.|.|:.||||||.|||.:..|..:||::|||||||||||.|::|...|            ....
Human   265 NNLKLICRAHQLVHEGYKFMFDEKLVTVWSAPNYCYRCGNIASIMVFKD------------VNTR 317

  Fly   297 EPHVTRRTPD------------YFL 309
            ||.:.|..||            |||
Human   318 EPKLFRAVPDSERVIPPRTTTPYFL 342

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mts	NP_476805.1	MPP_PP2A_PP4_PP6	9..293	CDD:277360	165/320 (52%)
PPP6C	NP_001116827.1	MPP_PP2A_PP4_PP6	5..326	CDD:277360	168/332 (51%)