DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment mts and PPP4C

DIOPT Version :9

Sequence 1:NP_001285724.1 Gene:mts / 45959 FlyBaseID:FBgn0004177 Length:309 Species:Drosophila melanogaster
Sequence 2:NP_001290432.1 Gene:PPP4C / 5531 HGNCID:9319 Length:307 Species:Homo sapiens


Alignment Length:307 Identity:199/307 - (64%)
Similarity:246/307 - (80%) Gaps:3/307 - (0%)


- Green bases have known domain annotations that are detailed below.


  Fly     5 ATTKDLDQWIEQLNECNQLTETQVRTLCDKAKEILSKESNVQEVKCPVTVCGDVHGQFHDLMELF 69
            |...|||:.||||..|..:.|::|:.||.||:|||.:|||||.|..|||||||:||||:||.|||
Human     2 AEISDLDRQIEQLRRCELIKESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELF 66

  Fly    70 RIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYRERITILRGNHESRQITQVYGFYDECL 134
            |:||..|:||||||||:||||:|||||..||:||||||.:|||::||||||||||||||||||||
Human    67 RVGGDVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYGFYDECL 131

  Fly   135 RKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDSLDHIRALDRLQEVPHEGPMCDLL 199
            ||||:..||:|.|::||||.|:|::||:|||:||||||||.:||.||.:||.|||||:|||||||
Human   132 RKYGSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPMCDLL 196

  Fly   200 WSDPDDRGGWGISPRGAGYTFGQDISETFNNTNGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPN 264
            ||||:|..|||:|||||||.||.|:...||..|.:.::.||||||||||.|..:..|:|::||||
Human   197 WSDPEDTTGWGVSPRGAGYLFGSDVVAQFNAANDIDMICRAHQLVMEGYKWHFNETVLTVWSAPN 261

  Fly   265 YCYRCGNQAALMELDDSLKFSFLQFDPAPR--RGEPHVTRRTPDYFL 309
            |||||||.||::|||:.|:..|:.|:.||:  ||.|. .:...||||
Human   262 YCYRCGNVAAILELDEHLQKDFIIFEAAPQETRGIPS-KKPVADYFL 307

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
mtsNP_001285724.1 MPP_PP2A_PP4_PP6 9..293 CDD:277360 189/283 (67%)
PPP4CNP_001290432.1 MPP_PP2A_PP4_PP6 6..290 CDD:277360 189/283 (67%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0639
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 1 1.010 - - QHG53795
OrthoDB 1 1.010 - - D349967at33208
OrthoFinder 1 1.000 - - FOG0000018
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
65.830

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