DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mts and ppa2

DIOPT Version :9

Sequence 1:	NP_001285724.1	Gene:	mts / 45959	FlyBaseID:	FBgn0004177	Length:	309	Species:	Drosophila melanogaster
Sequence 2:	NP_595940.1	Gene:	ppa2 / 2540072	PomBaseID:	SPBC16H5.07c	Length:	322	Species:	Schizosaccharomyces pombe

Alignment Length:	305	Identity:	240/305 - (78%)
Similarity:	274/305 - (89%)	Gaps:	0/305 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 ATTKDLDQWIEQLNECNQLTETQVRTLCDKAKEILSKESNVQEVKCPVTVCGDVHGQFHDLMELF 69
            ||..|:|:|||||.:|..|:|..|..|||||:|:|.:|:|||.|:.|||||||:|||||||||||
pombe    18 ATLGDVDRWIEQLKKCEPLSEADVEMLCDKAREVLCQENNVQPVRNPVTVCGDIHGQFHDLMELF 82

  Fly    70 RIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYRERITILRGNHESRQITQVYGFYDECL 134
            :|||..||.|||||||||||||:|||||:||||:|:||..|||||||||||||||||||||||||
pombe    83 KIGGDVPDMNYLFMGDYVDRGYHSVETVSLLVAMKLRYPNRITILRGNHESRQITQVYGFYDECL 147

  Fly   135 RKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDSLDHIRALDRLQEVPHEGPMCDLL 199
            ||||:|||||:||:||||.|||||::.:|||||||||||||||||:|.|||:|||||||||||||
pombe   148 RKYGSANVWKHFTNLFDYFPLTALIEDRIFCLHGGLSPSIDSLDHVRTLDRVQEVPHEGPMCDLL 212

  Fly   200 WSDPDDRGGWGISPRGAGYTFGQDISETFNNTNGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPN 264
            |||||||.||||||||||||||||||||||:.|||:|.:|||||||||:||.||.:|||||||||
pombe   213 WSDPDDRCGWGISPRGAGYTFGQDISETFNHANGLSLTARAHQLVMEGFNWAHDGDVVTIFSAPN 277

  Fly   265 YCYRCGNQAALMELDDSLKFSFLQFDPAPRRGEPHVTRRTPDYFL 309
            ||||||||||::|:||::...|||||||||.|||.:.||||||||
pombe   278 YCYRCGNQAAILEVDDTMNQVFLQFDPAPREGEPVIARRTPDYFL 322

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mts	NP_001285724.1	MPP_PP2A_PP4_PP6	9..293	CDD:277360	224/283 (79%)
ppa2	NP_595940.1	PTZ00239	22..322	CDD:173488	236/299 (79%)
ppa2	NP_595940.1	MPP_PP2A_PP4_PP6	22..306	CDD:277360	224/283 (79%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	364	1.000	Domainoid score	I148
eggNOG	1	0.900	-	-		E1_COG0639
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	525	1.000	Inparanoid score	I218
OMA	1	1.010	-	-		QHG53795
OrthoFinder	1	1.000	-	-		FOG0000018
OrthoInspector	1	1.000	-	-		oto102038
orthoMCL	1	0.900	-	-		OOG6_100547
Panther	1	1.100	-	-	LDO	PTHR45619
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R953
SonicParanoid	1	1.000	-	-		X621
TreeFam	1	0.960	-	-
	13	12.860