DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment mts and Ppp2ca

DIOPT Version :9

Sequence 1:	NP_001285724.1	Gene:	mts / 45959	FlyBaseID:	FBgn0004177	Length:	309	Species:	Drosophila melanogaster
Sequence 2:	NP_058735.1	Gene:	Ppp2ca / 24672	RGDID:	3380	Length:	309	Species:	Rattus norvegicus

Alignment Length:	309	Identity:	290/309 - (93%)
Similarity:	305/309 - (98%)	Gaps:	0/309 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MEDKATTKDLDQWIEQLNECNQLTETQVRTLCDKAKEILSKESNVQEVKCPVTVCGDVHGQFHDL 65
            |::|..||:|||||||||||.||:|:||::||:||||||:||||||||:||||||||||||||||
  Rat     1 MDEKLFTKELDQWIEQLNECKQLSESQVKSLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDL 65

  Fly    66 MELFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYRERITILRGNHESRQITQVYGFY 130
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat    66 MELFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYRERITILRGNHESRQITQVYGFY 130

  Fly   131 DECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDSLDHIRALDRLQEVPHEGPM 195
            |||||||||||||||||||||||||||||||||||||||||||||:|||||||||||||||||||
  Rat   131 DECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPM 195

  Fly   196 CDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNNTNGLTLVSRAHQLVMEGYNWCHDRNVVTIF 260
            ||||||||||||||||||||||||||||||||||:.|||||||||||||||||||||||||||||
  Rat   196 CDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIF 260

  Fly   261 SAPNYCYRCGNQAALMELDDSLKFSFLQFDPAPRRGEPHVTRRTPDYFL 309
            ||||||||||||||:|||||:||:|||||||||||||||||||||||||
  Rat   261 SAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAPRRGEPHVTRRTPDYFL 309

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mts	NP_001285724.1	MPP_PP2A_PP4_PP6	9..293	CDD:277360	268/283 (95%)
Ppp2ca	NP_058735.1	MPP_PP2A_PP4_PP6	9..293	CDD:277360	268/283 (95%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166337338
Domainoid	1	1.000	403	1.000	Domainoid score	I703
eggNOG	1	0.900	-	-		E1_COG0639
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H37660
Inparanoid	1	1.050	627	1.000	Inparanoid score	I819
OMA	1	1.010	-	-		QHG53795
OrthoDB	1	1.010	-	-		D349967at33208
OrthoFinder	1	1.000	-	-		FOG0000018
OrthoInspector	1	1.000	-	-		otm46313
orthoMCL	1	0.900	-	-		OOG6_100547
Panther	1	1.100	-	-	LDO	PTHR45619
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X621
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.770