DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mts and Ppef1

DIOPT Version :9

Sequence 1:	NP_001285724.1	Gene:	mts / 45959	FlyBaseID:	FBgn0004177	Length:	309	Species:	Drosophila melanogaster
Sequence 2:	XP_011246120.1	Gene:	Ppef1 / 237178	MGIID:	1097157	Length:	676	Species:	Mus musculus

Alignment Length:	308	Identity:	94/308 - (30%)
Similarity:	146/308 - (47%)	Gaps:	55/308 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 KAKEILSKESNVQEVKC----PVTVCGDVHGQFHDLMELFRIGGKSPDTN-YLFMGDYVDRGYYS 93
            :|:::|.:..|...||.    .:|:|||:||:..|||.:|...|...:.| |:|.||:||||..|
Mouse   174 EARKVLKQMPNFSHVKTFPAKEITICGDLHGKLDDLMLIFYKNGLPSENNPYVFNGDFVDRGNNS 238

  Fly    94 VETVTLLVALKVRYRERITILRGNHESRQITQVYGFYDECLRKY--GNANVWKYFTDLFDYLPLT 156
            :|.:.:|:...:.|...:.:.|||||...:...|||..|.|:||  ....:.:...:::.:||:.
Mouse   239 MEILMILLVCFLVYPSDLHLNRGNHEDFMMNLRYGFTKEILQKYKLHGRKILQVLEEVYTWLPIG 303

  Fly   157 ALVDGQIFCLHGGLSPSIDSLDHIRALDR-------------LQEV------------------P 190
            .::|.:|..:|||:|.|.| |:.:..|.|             .||.                  |
Mouse   304 TIIDNEILVIHGGISESTD-LNTLHQLQRNKMKSVLMPPVLGNQETGEKRNKSASNYVEPRKVEP 367

  Fly   191 HEGP-----------MCDLLWSDPDDRGGWGISP---RGAGYTFGQDISETFNNTNGLTLVSRAH 241
            .:.|           :.|:|||||  ||..|..|   ||.|..||.|::....:.|.|.::.|:|
Mouse   368 DKTPSEDLTKQEWEQIVDILWSDP--RGKKGCYPNTSRGGGCYFGPDVTSKVLSKNQLKMLIRSH 430

  Fly   242 QLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAALMELDDSLKFSFLQF 289
            :...:||...||..|:|:|||.||.....|:.|.:.|.......|.|:
Mouse   431 ECKPDGYEVSHDGKVITVFSASNYYEEGSNRGAYIRLSYGTMPQFFQY 478

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mts	NP_001285724.1	MPP_PP2A_PP4_PP6	9..293	CDD:277360	94/308 (31%)
Ppef1	XP_011246120.1	MPP_RdgC	144..479	CDD:277364	94/308 (31%)
		PTZ00183	518..660	CDD:185503
		EF-hand_7	595..663	CDD:372618
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0639
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000018
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810