DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mts and pph-5

DIOPT Version :9

Sequence 1:	NP_001285724.1	Gene:	mts / 45959	FlyBaseID:	FBgn0004177	Length:	309	Species:	Drosophila melanogaster
Sequence 2:	NP_001367002.1	Gene:	pph-5 / 180263	WormBaseID:	WBGene00012665	Length:	496	Species:	Caenorhabditis elegans

Alignment Length:	300	Identity:	116/300 - (38%)
Similarity:	165/300 - (55%)	Gaps:	8/300 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MEDKATTKDLDQWIEQLNECNQLTETQVRTLCDKAKEILSKESNVQEVKCPV----TVCGDVHGQ 61
            :|||.|.:.:.|.|:......:|.:.....:..:....:.....:.|:..|.    |:|||||||
Worm   181 LEDKITKEFVLQLIKTFKNQQKLHKKYAFKMLLEFYNYVKSLPTMVEITVPTGKKFTICGDVHGQ 245

  Fly    62 FHDLMELFRIGGKSPDTN-YLFMGDYVDRGYYSVETVTLLVALKVRYRERITILRGNHESRQITQ 125
            |:||..:|.|.|...:|| |||.||:||||.:||||:..::..|:.|.....:.||||||..:.:
Worm   246 FYDLCNIFEINGYPSETNPYLFNGDFVDRGSFSVETIFTMIGFKLLYPNHFFMSRGNHESDVMNK 310

  Fly   126 VYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSID-SLDHIRALDRLQEV 189
            :|||..|...|| ...:...||:.|.:|||..|::.:||..||||..... :|:.||..||.::.
Worm   311 MYGFEGEVKAKY-TQQMCDMFTETFCWLPLCHLINEKIFVCHGGLFKEDGVTLEDIRKTDRNRQP 374

  Fly   190 PHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNNTNGLTLVSRAHQLVMEGYNWCHDR 254
            |.||.|||||||||....|...|.||.|..||.|::..:..|||:..|.|:|::..|||...|:.
Worm   375 PDEGIMCDLLWSDPQPINGRSPSKRGVGCQFGPDVTSKWCETNGIEYVVRSHEVKPEGYEMHHNG 439

  Fly   255 NVVTIFSAPNYCYRCGNQAALMEL-DDSLKFSFLQFDPAP 293
            ...|:|||||||.:..|:.|.:.: .|:|...|..||..|
Worm   440 QCFTVFSAPNYCDQMNNKGAFITITGDNLTPRFTPFDAVP 479

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mts	NP_001285724.1	MPP_PP2A_PP4_PP6	9..293	CDD:277360	111/290 (38%)
pph-5	NP_001367002.1	PLN03088	29..>139	CDD:215568
		TPR repeat	33..57	CDD:276809
		TPR repeat	62..91	CDD:276809
		TPR repeat	96..124	CDD:276809
		MPP_PP5_C	176..490	CDD:277362	115/299 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910