DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mts and pef-1

DIOPT Version :9

Sequence 1:	NP_001285724.1	Gene:	mts / 45959	FlyBaseID:	FBgn0004177	Length:	309	Species:	Drosophila melanogaster
Sequence 2:	NP_741091.1	Gene:	pef-1 / 175257	WormBaseID:	WBGene00003969	Length:	707	Species:	Caenorhabditis elegans

Alignment Length:	338	Identity:	102/338 - (30%)
Similarity:	163/338 - (48%)	Gaps:	49/338 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MEDKATTK-DLD------------------QWIEQLNECNQLTETQVRTLCDKAKEILSKESNVQ 46
            :||.:.|. |:|                  :.||.......|....|..:..:|::|.....:|.
Worm   177 LEDTSPTNVDIDRNYKGPTLSLPLDKPQVAKMIEAFKVNKVLHPKYVLMILHEARKIFKAMPSVS 241

  Fly    47 EVKC----PVTVCGDVHGQFHDL-MELFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVR 106
            .:..    .||:|||:||:|.|| :.|::.|..|.|..|:|.||:||||..|:|.:.:|.||.:.
Worm   242 RISTSISNQVTICGDLHGKFDDLCIILYKNGYPSVDNPYIFNGDFVDRGGQSIEVLCVLFALVIV 306

  Fly   107 YRERITILRGNHESRQITQVYGFYDECLRKYGNAN--VWKYFTDLFDYLPLTALVDGQIFCLHGG 169
            ....|.:.|||||...:...|||..|...||.:.:  :.:...|:|.:||:..::|..||.:|||
Worm   307 DPMSIYLNRGNHEDHIMNLRYGFIKELSTKYKDLSTPITRLLEDVFSWLPIATIIDRDIFVVHGG 371

  Fly   170 LS--PSIDSLDHI--------------RALDRLQE-----VPHEGPMCDLLWSDP-DDRGGWGIS 212
            :|  ..:..||.|              :.::..:|     |.....|.|::|||| .::|.|...
Worm   372 ISDQTEVSKLDKIPRHRFQSVLRPPVNKGMESEKENSAVNVDEWKQMLDIMWSDPKQNKGCWPNV 436

  Fly   213 PRGAGYTFGQDISETFNNTNGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAALME 277
            .||.|..||.||:.:|...:|..|:.|:|:...|||.:.|:...:|:|||.||.....|:.|.::
Worm   437 FRGGGSYFGADITASFLEKHGFRLLVRSHECKFEGYEFSHNNTCLTVFSASNYYETGSNRGAYVK 501

  Fly   278 -LDDSLKFSFLQF 289
             :..|.:..|:|:
Worm   502 FIGKSKQPHFVQY 514

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mts	NP_001285724.1	MPP_PP2A_PP4_PP6	9..293	CDD:277360	99/329 (30%)
pef-1	NP_741091.1	MPP_RdgC	199..515	CDD:277364	97/316 (31%)
		PP2Ac	218..514	CDD:197547	94/295 (32%)
		EFh	634..699	CDD:238008
		EF-hand_7	634..698	CDD:290234
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000018
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910