Protein Alignment spir and mtrr

DIOPT Version :10

• Sequence 1: NP_724254.1
• Gene: spir / 45931
• FlyBaseID: FBgn0003475
• Length: 1020
• Species: Drosophila melanogaster
• Sequence 2: XP_031759354.1
• Gene: mtrr / 733716
• XenbaseID: XB-GENE-5824649
• Length: 719
• Species: Xenopus tropicalis
• Alignment Length: 885
• Identity: 148/885 - (16%)
• Similarity: 263/885 - (29%)
• Gaps: 290/885 - (32%)

  Fly   188 SSSGDSSVINRAFDNSNHHHHHQHHHPPLVVSHRKIISELAEIVYTALDYNLPEDEECQVSQELE 252
            :..|.|..|:........||.                       :||..|:|.:.::..:..|.:
 Frog    15 TQQGQSKAISEEIGQQAEHHG-----------------------FTADIYSLKDFKKFNLETERD 56

  Fly   253 NLFNFMTADETDDDCIDEGIDEGDKRWDDESEEERNDTKELEHIIETCRN--HIKTTLPENHYRA 315
            .:...::...|.|.             .|.:.....:.:..||.::...|  :....|.::.|..
 Frog    57 PVVIVISTTGTGDP-------------PDAAIRFLKEIQNKEHPVDYFANLKYAVLALGDSEYTY 108

  Fly   316 VCRALVTETIELRVFLQQVLNNEAGAEKLIKASESSATTQQELAKLGFNDWAR-FWVQVIDELRR 379
            .|..  .:.|:.|:       .|.||:...:...:......||.   .:.|.. .|..:..|...
 Frog   109 FCNG--GKIIDWRL-------QELGAKHFYETGYADDCVGLELV---VDPWIEGLWTALHSEFIP 161

  Fly   380 GVRLKKSNHERTPIEYELTPYEILMGDIRAKKYQLRKVMVNGDIPPRVKKDAHAMILEFIRSRPP 444
            ....|.::|               |.::..:|      ....::|..::....|:.||. ...|.
 Frog   162 RTEKKNTDH---------------MKNMSTEK------PATDEVPENLELRIQAINLEH-SVLPK 204

  Fly   445 LKKASDRQLGPPRMCEPSPREQLMESIRKGKELKQITPPEAPTLRERVLPSANSTLSRSRQRLIK 509
            ...|.:......|:.:||    |:.|   |..|.|      ..|...||||....:.........
 Frog   205 YSLAENTGSESNRVIKPS----LLHS---GSLLSQ------SNLNVPVLPSPYLDVCVLESEGQS 256

  Fly   510 VDFSKFQDDDLFYDENSISSSHSTAATHQHHPHFAEMHRCSQPKMPPYPFGGYMVPSQARQDCRE 574
            .|.|....::..::.:.|.:...|:|                                   |..:
 Frog   257 TDLSLLYPEEKIFNISIIQAKELTSA-----------------------------------DAVK 286

  Fly   575 TASLMRPRRTMEPAKQVPPPEEPSFTKDEYHKFYDTALESYDLATQCESRRASLRRHTIVGCQSN 639
            |. ||........:.:..|.:..|......|:..:..||...||   |.|          .||.:
 Frog   287 TV-LMLELDISNTSAEFQPGDSFSIICPNPHEEVEMLLEKLTLA---EKR----------DCQVH 337

  Fly   640 LDETHSMPPTRPESRQSDDVSKETPKRSPAEQTHPSDEGSSTSSLGPWNKSFMDKQTWMERGDDR 704
            |                 .|...|.|:           |:|.....|...|.....||
 Frog   338 L-----------------GVKLGTKKK-----------GASVPGYIPEGCSLQFIFTW------- 367

  Fly   705 LSVTLAEIVHIRSVMTKAELEGLPMDVRVKEDVEKRRVCFLCLR---TRFSFF------------ 754
                   .:.||:|..||.:..|.  .......||||:..||.:   :.::.|
 Frog   368 -------CLEIRAVPKKAMIRALV--EHTSNAAEKRRLQELCSKQGGSDYNHFIRDNSISILDLL 423

  Fly   755 ----------------GPWGIQCKLCQRTVCAKCYTKMRIPS----EHFRNVPLVLISPSLLSSP 799
                            |..|::.:.......|.|:.::.||.    ||.         |.|.:.|
 Frog   424 NVFPSCSPPLNLLIATGNTGVKQQKISSPQKAICFCEVHIPQNPKLEHL---------PKLQARP 479

  Fly   800 ASSSTPSPSHHAQQAHSSST----GNIMDDQFPK---------SLIERLLRS---ESDRKTRSTV 848
            .|::: ||.:|..:.|...|    ....|...|:         .|:..:..:   :.|...:.::
 Frog   480 YSAAS-SPLYHPGKVHIVFTVVELPTCPDRPAPRKGVCTGWLAELVSHMYDTAELKKDFPPKISI 543

  Fly   849 GSAPSSPKHQRSNMSTPGISVGPGASSSSAAATGQAVEALHDQ---------------ATMSSSY 898
            .:.||:..|...:.|.|.:.||||...:......|..|.|.:|               .:..:.|
 Frog   544 FARPSTSFHLPRDPSVPILMVGPGTGIAPFIGFLQHREKLKEQNKERIFGDTWLFFGCRSHENEY 608

  Fly   899 SAAMRPSGVHQQQKQHYNNA-------MSRSMEGPRSLPVHSPAYRPLSNNSTLERKSRFSRGFN 956
                    :.:|:.:|:.::       :..|.:.|.:..|.||.|               .:.|
 Frog   609 --------LFRQELRHFTDSGVLTHLKVCFSRDPPINAGVVSPKY---------------VQDF- 649

  Fly   957 LFSSGSHLAQTQEQKENLRGEQVTVCNDCQGLVNEITSSV 996
            |....|.:|:.. .|||   ..:.||.|.:.:..::..::
 Frog   650 LKICSSDIAKVL-TKEN---GSIYVCGDAKNMAKDVNDAL 685

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spir	NP_724254.1	KIND	90..327	CDD:214801	20/140 (14%)
		WH2_Spire_1-2_r1	357..388	CDD:409208	6/31 (19%)
		actin-binding sequence	383..386	CDD:409208	1/2 (50%)
		WH2_Spire1_r2-like	394..425	CDD:409221	2/30 (7%)
		actin-binding sequence	414..417	CDD:409221	0/2 (0%)
		WH2_DmSpire_r3-like	427..452	CDD:409211	5/24 (21%)
		WH2_DmSpire_r4	459..487	CDD:409212	7/27 (26%)
		FYVE_SPIR	739..774	CDD:277287	10/65 (15%)
mtrr	XP_031759354.1	Flavodoxin_1	11..147	CDD:425562	26/179 (15%)
		methionine_synthase_red	272..718	CDD:99800	94/545 (17%)