DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment shi and DRP4A

DIOPT Version :9

Sequence 1:	NP_001259588.1	Gene:	shi / 45928	FlyBaseID:	FBgn0003392	Length:	896	Species:	Drosophila melanogaster
Sequence 2:	NP_176253.1	Gene:	DRP4A / 842348	AraportID:	AT1G60530	Length:	301	Species:	Arabidopsis thaliana

Alignment Length:	258	Identity:	91/258 - (35%)
Similarity:	148/258 - (57%)	Gaps:	15/258 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 LITIVNKLQDAFTSLGVHMQ-LDLPQIAVVGGQSAGKSSVLENFVGKDFLPRGSGIVTRRPLILQ 67
            |:..|::|:    :|.|..: :.||.|.|||.||:|||||||:..|.: ||||.||.||.||:::
plant    43 LLDTVDRLR----NLNVMREGIQLPTIVVVGDQSSGKSSVLESLAGIN-LPRGQGICTRVPLVMR 102

  Fly    68 LINGVTEYGE-FLHIKGKKFSSFDE-IRKEIEDETDRVTGSNKGISNIPINLRVYSPHVLNLTLI 130
            |....:...| :|....|...:.:| :.:.|...||.:.|:.:|:|:.|:.|.|...:|.:||::
plant   103 LQRSSSPEPEIWLEYSDKVVPTDEEHVAEAICAATDVIAGTGEGVSDTPLTLSVKKNNVPDLTMV 167

  Fly   131 DLPGLTKVAIGDQPVDIEQQIKQMIFQFIRKETCLILAVTPANTDLANSDALKLAKEVDPQGVRT 195
            ||||:|:|.:..||.:|.:||.:||.::|..:..:||.|..|..|....::::::::||..|.||
plant   168 DLPGITRVPVNGQPENIYEQISRMIMKYIEPQESIILNVLSATVDFTTCESIRMSRQVDKTGERT 232

  Fly   196 IGVITKLDLMDEGTDARDILENKLLPLRRGYIGVVNRSQKDIEGRKDIHQALAAERKFFLSHP 258
            :.|:||.|:..||...:...::..:.|  |||.|.||.     |.:...:|...|...|.:||
plant   233 LAVVTKADMAPEGLLQKVTADDVSIGL--GYICVRNRI-----GEETYEEARVQEDLLFRTHP 288

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
shi	NP_001259588.1	DYNc	1..240	CDD:197491	85/238 (36%)
		CrfC	73..>498	CDD:223771	59/188 (31%)
		Dynamin_M	212..498	CDD:279383	13/47 (28%)
		PH_dynamin	512..644	CDD:269958
		PH	552..638	CDD:278594
		GED	664..755	CDD:128597
		DUF4527	<758..819	CDD:291689
		Drf_FH1	<761..>846	CDD:283903
DRP4A	NP_176253.1	DLP_1	60..300	CDD:206738	86/237 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0699
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810