Protein Alignment shi and mfn1b

DIOPT Version :10

• Sequence 1: NP_001259588.1
• Gene: shi / 45928
• FlyBaseID: FBgn0003392
• Length: 896
• Species: Drosophila melanogaster
• Sequence 2: XP_073771670.1
• Gene: mfn1b / 393620
• ZFINID: ZDB-GENE-040426-1553
• Length: 745
• Species: Danio rerio
• Alignment Length: 511
• Identity: 100/511 - (19%)
• Similarity: 185/511 - (36%)
• Gaps: 152/511 - (29%)

  Fly     2 DSLITIVNKLQ----DAFTS-LGV--------HMQLDLPQIAVVGGQSAGKSSVLENFVGKDFLP 53
            :||..|.||.|    :::|| |.:        ||     ::|..|..|.|||:|:...:....||
Zfish    44 ESLENIANKDQLDEIESYTSKLSIIQEVLARRHM-----KVAFFGRTSNGKSTVINAMLRDRVLP 103

  Fly    54 RGSGIVTRRPLILQLINGVTEYGEFLHIKG----KKFSSFDEIRKEIEDETDRVTGSNKGISNIP 114
            .|.|..|.   ....:.|..|...||..:|    |...:.:::...:..:.....|
Zfish   104 SGIGHTTN---CFLSVEGTDEDKAFLKTEGSEEEKSIKTVNQLAHALHMDESLDAG--------- 156

  Fly   115 INLRVYSPHVL------NLTLIDLPGLTKVAIGDQPVDIEQQIKQMIFQFIRKETCLILAVTPAN 173
            ..::|:.|...      :|.|:|.||          .|:..::...|.:|.......:|.....:
Zfish   157 CLVKVFWPKTKCALLRDDLVLVDSPG----------TDVTTELDSWIDKFCLDADVFVLVANSES 211

  Fly   174 TDLANSDA-------LKLAKEVDPQGVRTIGVITKLDLMDEGTDARDILENKLLPLRRGYIGVVN 231
            | |.|::.       .||:|             ..:.:::...||.        .....|:..|.
Zfish   212 T-LMNTEKHFFHKVNEKLSK-------------PNIFILNNRWDAS--------AAEPEYMEDVR 254

  Fly   232 RSQKD------IEGRKDIHQALAAERKFFLSHPSYRHMADRLGTPYLQRVLNQQLTNHIRDTLP- 289
            :...|      :|..|.:.:|.|..|.||:|               .:.|||.::..  ...:|
Zfish   255 KQHTDRCVNFLVEELKVVDRAQAPNRIFFVS---------------AKEVLNSRMQR--AQGMPE 302

  Fly   290 -------GLRDKLQKQMLTLEKEVEE-FKHFQPGDASIKTKAMLQMIQQLQSDFERTIEGSGSAL 346
                   |.:|:| |:....|:..|| ..|     :::|||.....|:..|  ...|::.    :
Zfish   303 TGGALAEGFQDRL-KEFQNFERSFEECISH-----SAVKTKFEQHTIRAKQ--ITETVKD----I 355

  Fly   347 VNTNELSGGAKINRIFHERLRFEIVKMACDEKE-LRREISFAIRNIHGIRVGLFTPDMAFEAIVK 410
            ::...::...|  |:           ::.:|:| |...:.| :||    ::.|...|      :|
Zfish   356 MDQINITAAEK--RV-----------VSLEEREYLIDRLDF-VRN----QLNLLIQD------IK 396

  Fly   411 RQIALLKEPVIKCVDLVVQE----LSVVVRMCTAKMSRYPRLREETERIITTHVRQ 462
            ::|..:.|.|...|...:.|    |||::....:.....|::.:..:..:.:|:.|
Zfish   397 KKIKAITEEVENKVSNAMAEEICRLSVIIDEFRSDFHPSPQMLKMYKSDLLSHIEQ 452

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
shi	NP_001259588.1	DYNc	1..240	CDD:197491	53/273 (19%)
		Dynamin_M	210..498	CDD:460033	53/273 (19%)
		PH_dynamin	512..644	CDD:269958
		GED	664..755	CDD:128597
		FAP	725..>855	CDD:429334
mfn1b	XP_073771670.1	None