Protein Alignment shi and fzo-1

DIOPT Version :9

• Sequence 1: NP_001259588.1
• Gene: shi / 45928
• FlyBaseID: FBgn0003392
• Length: 896
• Species: Drosophila melanogaster
• Sequence 2: NP_495161.1
• Gene: fzo-1 / 173990
• WormBaseID: WBGene00001509
• Length: 774
• Species: Caenorhabditis elegans
• Alignment Length: 615
• Identity: 120/615 - (19%)
• Similarity: 207/615 - (33%)
• Gaps: 231/615 - (37%)

  Fly     2 DSLITIVNKLQDAFTSLGVHMQLDLPQIAVVGGQSAGKSSVLENFVGKDFLPRGSGIVTRRPLIL 66
            ||:.||:    |.|       |.|..::...|..|.|||:.:...:.:..||:|.|..|  ...|
 Worm    87 DSIKTIM----DTF-------QRDNMKVVFFGRTSNGKSTTINAMLHEKVLPQGMGHTT--CCFL 138

  Fly    67 QLINGVTEYGEF----------LHIKGKKFSSFDEIRKEIEDETDRVTGSNKGISNIPIN----- 116
            |:.....|.|..          :.:.||       |...:.||.          |::|..
 Worm   139 QVEGSEGEVGHLQLDDNPQKIDMKMLGK-------IGHALSDEN----------SDLPAMGQDSL 186

  Fly   117 LRVYSP--------HVL--NLTLIDLPGLTKVAIGDQPVDIEQQIKQMIFQFIRKETCL----IL 167
            |:|:.|        .:|  ::.::|.||          ||:..:....|     .:.||    .:
 Worm   187 LKVFHPKKSESGECRLLQNDVVILDSPG----------VDLSPEFDSWI-----DKHCLDADVFV 236

  Fly   168 AVTPANTDLANSDA---LKLAKEVDPQGVRTIG---------------------------VITKL 202
            .|:.|.:.|..::.   |::||::....|..:.                           ::.:|
 Worm   237 LVSNAESTLTQAEKNFFLRVAKKLSKPNVFILNNRWDASAAETENIEDVKKQHLTRFRQFLVDEL 301

  Fly   203 DLMDEG--------TDARDILENKLLPLRRGYIGVVNRSQKDIEGRKDIHQALAAERKFFLSHPS 259
            ::..|.        ..:|::||::|...     |:|.::.: .||    |...|.|.:.|..|
 Worm   302 EVCSEREVNDRIFFVSSREVLESRLKAR-----GLVQKAYQ-AEG----HGTRALEFQNFERH-- 354

  Fly   260 YRHMADR--LGTPY-------------LQRVLNQQLTNHIRDTLPGLRDKLQKQMLTLEKEVEE- 308
            :.|...|  :.|.:             ::..||..||:....     |.|||..:....:...|
 Worm   355 FEHCISRSAIHTKFEAHNRRAHEMIGKMRLNLNSVLTSAAEQ-----RSKLQNNLNESTRTFNEC 414

  Fly   309 ---FKHFQPGDASIKTKAMLQMIQQLQSD----------------------FERTIEGSGSALVN 348
               |..|:        ||..:..:||:::                      ||:..:||.|.:..
 Worm   415 RVNFTQFE--------KAYREQTEQLRAEVHLKVSADFFEEIARLDAIIDRFEQPFDGSSSGMTK 471

  Fly   349 TNE---------LSG-------GAKINRIFH-ERLRFEIVKMACDEK---------ELRREISFA 387
            ..|         ||.       |..::||:: |...|:.|.....|.         ..|....|:
 Worm   472 YKEDLAIFVDKCLSSDLEARCTGGLMSRIWNLENDMFQYVTKILAEPYQNKLEEVWRYRAPFKFS 536

  Fly   388 IRNIHGIRVGLFTPDMAF------EAIVKRQIALLK-EPVIKCVDLVVQELSVVVRMCTAKMSRY 445
            |.......|..|..|:.|      .||::|.||... :||......::..||
 Worm   537 ICVDVPALVNDFHEDLEFRFTFGLHAIIRRIIAYRSGQPVTAINTNLLTPLS------------- 588

  Fly   446 PRLREETERIITTHVRQREHSC--KEQILL 473
              |::::|:   ..||..|.|.  :||.::
 Worm   589 --LKQQSEK---NSVRDAEASAASEEQAMM 613

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
shi	NP_001259588.1	DYNc	1..240	CDD:197491	57/304 (19%)
		CrfC	73..>498	CDD:223771	100/544 (18%)
		Dynamin_M	212..498	CDD:279383	70/338 (21%)
		PH_dynamin	512..644	CDD:269958
		PH	552..638	CDD:278594
		GED	664..755	CDD:128597
		DUF4527	<758..819	CDD:291689
		Drf_FH1	<761..>846	CDD:283903
fzo-1	NP_495161.1	DLP_2	101..359	CDD:206739	56/303 (18%)
		Fzo_mitofusin	609..767	CDD:282633	2/5 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0699
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900