Protein Alignment fzr and SPAC13G6.08

DIOPT Version :9

• Sequence 1: NP_524852.2
• Gene: fzr / 45922
• FlyBaseID: FBgn0262699
• Length: 478
• Species: Drosophila melanogaster
• Sequence 2: NP_592834.1
• Gene: SPAC13G6.08 / 2542840
• PomBaseID: SPAC13G6.08
• Length: 535
• Species: Schizosaccharomyces pombe
• Alignment Length: 531
• Identity: 141/531 - (26%)
• Similarity: 225/531 - (42%)
• Gaps: 155/531 - (29%)

  Fly    16 PVARNLF--------NNFESSTTPTSLDRFIPCRAYNNWQTNFASINKSNDNSPQTSKKQRDCGE 72
            |:::|||        .|.:..|:...||||||..  :|..|  .|:.:.:..|.....|.::..|
pombe    59 PISKNLFQSYPKGSYRNSQRLTSRNGLDRFIPMT--SNKDT--ISLGRHSSLSRNLVNKTKNASE 119

  Fly    73 TARDSLAYSCLLKNELLGSAIDDVKTAGEERNENAYTPAAKRSLFKYQSPTKQDYNGECPYSLSP 137
            |.:..|.|:..:                 ||::|.:|         |....|.|...:||..::
pombe   120 TYQQLLEYALEV-----------------ERDDNVFT---------YAKLQKSDMTQKCPTMVA- 157

  Fly   138 VSAKSQKLLRSPRKATRKISRIPFKVLDAPELQDDFYLNLVDWSSQNVLAVGLGSCVYLWSACTS 202
             |.|..|...:.:|.....:.:||::||||||:||||.:|:.||.:..||:||...:||||....
pombe   158 -SEKDNKGKLNEKKNRSPENLLPFRILDAPELRDDFYTSLLSWSPKGDLAIGLAENIYLWSKELG 221

  Fly   203 QVTRLCDLSPDANTVTSVSWNERGNTVAVGTHHGYVTVWDVAANKQINKLN-GHSARVGALAWNS 266
            . ||:  |......|:||:::..|:.:|||...|.:..|.  .|:::.::: .|...:|.|||.
pombe   222 P-TRV--LEESIYDVSSVAYSYNGDILAVGRVDGTLQFWQ--DNERVPRISIHHPGDIGVLAWK- 280

  Fly   267 DILSSGSRDRWIIQRDTRTPQLQSERRLAG-----------------------------HRQEVC 302
                               |.|::.|.|.|                             |.::||
pombe   281 -------------------PVLETNRLLVGKGNGNIFVYDIIWSESTSKAVLVATITNAHDEQVC 326

  Fly   303 GLKWSPDNQYLASGGNDNR------------LYVWNQHSVNPVQSYTEHMAAVKAIAWSPHHHGL 355
            ||.|:.|....||||||||            ||||.|:            |||||:::.|....|
pombe   327 GLTWNHDGSQFASGGNDNRVCLFKGSDLRQPLYVWQQN------------AAVKALSFCPWQRSL 379

  Fly   356 LASGGGTADRCIRFWNTLTGQPMQCVDTGSQVCNLAWSKHSSELVSTHGYS----QNQILVWKYP 416
            ||:|.|:.|:.|||:|...|:.:..:..|:|:.::.||....|...|.|||    |::..|:.:|
pombe   380 LATGAGSHDKHIRFYNCFNGKKIDELYCGAQITSIHWSPKYREFSVTFGYSLETVQHRFAVYSWP 444

  Fly   417 SL---------------------TQVAKLTGHSYRVLYLALSPDGEAIVTGAGDETLRFWNVFSK 460
            .|                     :|:.:.||.....         ::|:..:.:||::|:::  .
pombe   445 QLECLVSVLPSVPDIRCVHSVLTSQLNETTGRCEMT---------DSIIIASSNETIKFFDL--S 498

  Fly   461 ARSQKENKSVL 471
            ..|...|..||
pombe   499 EESSWHNSRVL 509

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fzr	NP_524852.2	WD40	<174..469	CDD:225201	94/361 (26%)
		WD40	178..456	CDD:238121	90/344 (26%)
		WD40 repeat	217..254	CDD:293791	10/37 (27%)
		WD40 repeat	260..296	CDD:293791	8/35 (23%)
		WD40 repeat	301..337	CDD:293791	19/47 (40%)
		WD40 repeat	344..382	CDD:293791	14/37 (38%)
		WD40 repeat	387..425	CDD:293791	12/62 (19%)
		WD40 repeat	431..457	CDD:293791	4/25 (16%)
SPAC13G6.08	NP_592834.1	WD40	<195..498	CDD:225201	91/350 (26%)
		WD40 repeat	195..232	CDD:293791	14/39 (36%)
		WD40	<213..418	CDD:295369	67/241 (28%)
		WD40 repeat	234..269	CDD:293791	9/36 (25%)
		WD40 repeat	274..302	CDD:293791	9/47 (19%)
		WD40 repeat	325..362	CDD:293791	17/36 (47%)
		WD40 repeat	367..404	CDD:293791	15/36 (42%)
		WD40 repeat	462..497	CDD:293791	7/43 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0305
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810