Protein Alignment fzr and srw1

DIOPT Version :10

• Sequence 1: NP_524852.2
• Gene: fzr / 45922
• FlyBaseID: FBgn0262699
• Length: 478
• Species: Drosophila melanogaster
• Sequence 2: NP_594674.1
• Gene: srw1 / 2542824
• PomBaseID: SPAC144.13C
• Length: 556
• Species: Schizosaccharomyces pombe
• Alignment Length: 487
• Identity: 212/487 - (43%)
• Similarity: 286/487 - (58%)
• Gaps: 66/487 - (13%)

  Fly    35 DRFIPCR-AYNNWQTNFASINKSNDNSPQTSKKQRDCGETARDSLA---YSCLLKNELLG----- 90
            |||||.| |.....|.|..:     ..|.|..|:       :.|:|   ::.||::||.|
pombe    74 DRFIPSRDASTELWTGFTKV-----EGPLTPVKK-------KQSVADRNFTTLLRSELFGSNDET 126

  Fly    91 ---------------------SAIDDVKTAGEERNENAYTPAA---------KRSLFKYQSPTK- 124
                                 |.|||::........:::|.::         .|.:|.|.||..
pombe   127 FNNSPIATPNTTIGVSTPRTDSGIDDIELTQRTPPSSSHTSSSILQNTPVTPSRKIFHYLSPRDR 191

  Fly   125 -----------QDYNGECPYSLSPVSAKSQKLLRSPRKATRKISRIPFKVLDAPELQDDFYLNLV 178
                       ||......||||||.:.::.|:.:.|...|::..||::|||||.|..||||||:
pombe   192 NKSSYGKKAQYQDNPNRTIYSLSPVRSITKDLISASRLEGRELPSIPYRVLDAPGLAGDFYLNLL 256

  Fly   179 DWSSQNVLAVGLGSCVYLWSACTSQVTRLCDLSPDANTVTSVSWNERGNTVAVGTHHGYVTVWDV 243
            ||...|:|||.|.|.|||||..:|:||.:.:..| .:||||:.|.:||..:|||||:|.|.:||.
pombe   257 DWGQCNMLAVALASRVYLWSGISSEVTVMHNFYP-TDTVTSLRWVQRGTHLAVGTHNGSVEIWDA 320

  Fly   244 AANKQINKLNGHSARVGALAWNSDILSSGSRDRWIIQRDTRTPQLQSERRLAGHRQEVCGLKWSP 308
            |..|:...::||:.|||||:||..:||||.||..|:.||.|.|: ...|.|..||||||||:|:.
pombe   321 ATCKKTRTMSGHTERVGALSWNDHVLSSGGRDNHILHRDVRAPE-HYFRVLTAHRQEVCGLEWNS 384

  Fly   309 DNQYLASGGNDNRLYVWNQHSVNPVQSYTEHMAAVKAIAWSPHHHGLLASGGGTADRCIRFWNTL 373
            :...||||||||.|.||::....|:.|:..|:||||||.||||..|:||||||||||.|:.|||.
pombe   385 NENLLASGGNDNALMVWDKFEEKPLYSFHNHIAAVKAITWSPHQRGILASGGGTADRTIKLWNTQ 449

  Fly   374 TGQPMQCVDTGSQVCNLAWSKHSSELVSTHGYSQNQILVWKYPSLTQVAKLTGHSYRVLYLALSP 438
            .|..:..:|||||||||.|||.::|.:||||:.:|::.:|.|||:::|..|.||:.||||||:||
pombe   450 RGSMLHNIDTGSQVCNLLWSKQTNEFISTHGFMENEVALWNYPSVSRVGTLKGHTDRVLYLAMSP 514

  Fly   439 DGEAIVTGAGDETLRFWNVF-SKARSQKENKS 469
            :||.|||||.|||||||.:| ||::......|
pombe   515 NGENIVTGAADETLRFWKLFDSKSKHSASTMS 546

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fzr	NP_524852.2	WD40	<194..457	CDD:441893	146/262 (56%)
		WD40 repeat	217..254	CDD:293791	17/36 (47%)
		WD40 repeat	260..296	CDD:293791	18/35 (51%)
		WD40 repeat	301..337	CDD:293791	18/35 (51%)
		WD40 repeat	344..382	CDD:293791	23/37 (62%)
		WD40 repeat	387..425	CDD:293791	18/37 (49%)
		WD40 repeat	431..457	CDD:293791	21/25 (84%)
srw1	NP_594674.1	WD40	<290..533	CDD:441893	138/244 (57%)
		WD40 repeat	295..331	CDD:293791	16/35 (46%)
		WD40 repeat	336..370	CDD:293791	18/34 (53%)
		WD40 repeat	378..413	CDD:293791	17/34 (50%)
		WD40 repeat	419..455	CDD:293791	24/35 (69%)
		WD40 repeat	463..501	CDD:293791	18/37 (49%)
		WD40 repeat	507..531	CDD:293791	19/23 (83%)