Protein Alignment ort and Gabrp

DIOPT Version :10

• Sequence 1: NP_524406.1
• Gene: ort / 45910
• FlyBaseID: FBgn0003011
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: NP_112291.1
• Gene: Gabrp / 81658
• RGDID: 620532
• Length: 440
• Species: Rattus norvegicus
• Alignment Length: 512
• Identity: 136/512 - (26%)
• Similarity: 228/512 - (44%)
• Gaps: 112/512 - (21%)

  Fly     8 LVICTICMKHYAK------GEFQQSLAITDILP----EDIKR-YDKMRPPKKEGQPTIVYFHVTV 61
            |.:..:|:...|:      .:|...::.:|.|.    |::.. |:|...|...|.|..:...:.:
  Rat     5 LYLAFVCLNLLAQRMCIQGNQFNVEVSRSDKLSLPGFENLTAGYNKFLRPNFGGDPVRIALTLDI 69

  Fly    62 MGLDSIDENSMTYVADVFFAQTWKDHRLRLPEN--MTQEYRLLEVDWLKNMWRPDSFFKNAKSVT 124
            ..:.||.|::|.|.|.::..|.|.|.||....|  .|.:.||:|.     :|.||::...:|...
  Rat    70 ASISSISESNMDYTATIYLRQRWTDPRLVFEGNKSFTLDARLVEF-----LWVPDTYIVESKKSF 129

  Fly   125 FQTMTIPNHYMWLYKDKTILYMVKLTLKLSCIMNFAIYPHDTQECKLQMESLSHTTDDLIFQW-- 187
            ...:|:.|..:.|:.:.|:||.:::|..::|.|:.:.||.|||.||||:||..:..:|:.|.|
  Rat   130 LHEVTVGNRLIRLFSNGTVLYALRITTTVTCNMDLSKYPMDTQTCKLQLESWGYDGNDVEFSWLR 194

  Fly   188 --DPTTPLVVDENIELPQVALIRNETADCTQVYSTGNFTCLEVVFTLKRRLVYYVFNTYIPTCMI 250
              |....|   ||:.|.|..:.:..|........|||:|.|.:.|.|:|.::|::..||:|:..:
  Rat   195 GNDSVRGL---ENLRLAQYTIQQYFTLVTVSQQETGNYTRLVLQFELRRNVLYFILETYVPSTFL 256

  Fly   251 VIMSWVSFWIKPEAAPARVTLGVTSLLTLSTQHAKSQSSLPPVS-YLKAVDAFMSVCTVFVFMAL 314
            |::|||||||..|:.|||..:|||::|:::|....|::|||..: ::||:|.::.:|..|||.||
  Rat   257 VVLSWVSFWISLESVPARTCIGVTTVLSMTTLMIGSRTSLPNTNCFIKAIDVYLGICFSFVFGAL 321

  Fly   315 MEYCLINIVLSDTPIPKPMAYPPKPVAGDGPKKEGEGAPPGGSNSTASKQQATMLPLADEKIEKI 379
            :||.:.:.          .:.....|...||.|:.|..                         .|
  Rat   322 LEYAVAHY----------SSLQQMAVKDRGPAKDSEEV-------------------------NI 351

  Fly   380 EKIFDEMTKNRRIVTTTRRVVRPPLDADG----------------PWIPRQE-SRIILTPTIAPP 427
            ..|.     |..|.:..|::....::..|                .::.|:: .|||...||..|
  Rat   352 TNII-----NSSISSFKRKISFASIEISGDNVNYSDLTMKASDKFKFVFREKIGRIIDYFTIQNP 411

  Fly   428 PPPPQPAAPEPELPKPKLTPAQERLKRAIYIDRSSRVLFPALFASLNGIYWCVFYEY 484
            .                            .:||.|::|||.:|...|..|| .:|.|
  Rat   412 S----------------------------NVDRYSKLLFPLIFMLANVFYW-AYYMY 439

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ort	NP_524406.1	LIC	31..481	CDD:455710	130/478 (27%)
		LGIC_ECD_HisCl	51..235	CDD:349793	58/189 (31%)
		Cys-loop	155..169	CDD:349793	7/13 (54%)
Gabrp	NP_112291.1	LIC	43..437	CDD:455710	127/470 (27%)
		LGIC_ECD	60..241	CDD:475126	58/188 (31%)