Protein Alignment ort and Gabrg3

DIOPT Version :10

• Sequence 1: NP_524406.1
• Gene: ort / 45910
• FlyBaseID: FBgn0003011
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: NP_077346.3
• Gene: Gabrg3 / 79211
• RGDID: 621735
• Length: 467
• Species: Rattus norvegicus
• Alignment Length: 501
• Identity: 149/501 - (29%)
• Similarity: 221/501 - (44%)
• Gaps: 116/501 - (23%)

  Fly    25 QSLAITDILPEDIKRYDKMRPPKKEGQPTIVYFHVTVMGLDSIDENSMTYVADVFFAQTWKDHRL 89
            |...:|.||.:.::.|||...|....:||::...:.|..:..:...:|.|..|:||||||.|.||
  Rat    43 QDTDVTLILNKLLREYDKKLRPDIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQTWTDSRL 107

  Fly    90 RLPENMTQEYRLLEVDWLKNMWRPDSFFKNAKSVTFQTMTIPNHYMWLYKDKTILYMVKLTLKLS 154
            |.  |.|.:...|..:.:..:|.||:.|:|:|:.....:|.||..:.::.|..|||.::||:...
  Rat   108 RF--NSTMKILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTLRLTINAE 170

  Fly   155 CIMNFAIYPHDTQECKLQMESLSHTTDDLIFQWDPTTPLVVDE-NIELPQVAL--IRNETADCTQ 216
            |.:....:|.|...|.|...|..:..:::|::|...:....|: :..|.|...  :||.|...|.
  Rat   171 CQLQLHNFPMDAHACPLTFSSYGYPKEEMIYRWRKNSVEAADQKSWRLYQFDFMGLRNTTEIVTT 235

  Fly   217 VYSTGNFTCLEVVFTLKRRLVYYVFNTYIPTCMIVIMSWVSFWIKPEAAPARVTLGVTSLLTLST 281
              |.|::..:.:.|.|.||:.|:...||||..:.|::||||||||.:|.|||.|||:|::||::|
  Rat   236 --SAGDYVVMTIYFELSRRMGYFTIQTYIPCILTVVLSWVSFWIKKDATPARTTLGITTVLTMTT 298

  Fly   282 QHAKSQSSLPPVSYLKAVDAFMSVCTVFVFMALMEYCLINIVLSDTPIPKPMAYPPKPVAGDGPK 346
            ....::.|||.|||:.|:|.|::||.:|||.|||||..:|...|   ..||
  Rat   299 LSTIARKSLPRVSYVTAMDLFVTVCFLFVFAALMEYATLNYYSS---CRKP-------------- 346

  Fly   347 KEGEGAPPGGSNSTASKQQATML-PLADEKIEKIEKIFDEMTKNRRIVTTTRRVVRPPLDADGPW 410
                         |..|::.::| |                       .:||            |
  Rat   347 -------------TIRKKKTSLLHP-----------------------DSTR------------W 363

  Fly   411 IPRQESRIILTPTIAPP--------PPPPQPAAPEPELPKPKL--TPAQERL------------- 452
            ||   .||.|.   ||.        ||||........:...:.  |...|.|
  Rat   364 IP---DRISLQ---APSNYSLLDMRPPPPVMITLNNSMYWQEFEDTCVYECLDGKDCQSFFCCYE 422

  Fly   453 --------KRAIYIDRS-----SRVLFPALFASLNGIYWCVFYEYL 485
                    :..|:||.|     |||.||..|...|.:|| |.|.||
  Rat   423 ECKSGSWRRGRIHIDVSELDSYSRVFFPTSFLLFNLVYW-VGYLYL 467

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ort	NP_524406.1	LIC	31..481	CDD:455710	143/489 (29%)
		LGIC_ECD_HisCl	51..235	CDD:349793	53/186 (28%)
		Cys-loop	155..169	CDD:349793	3/13 (23%)
Gabrg3	NP_077346.3	LIC	50..464	CDD:455710	144/489 (29%)
		LGIC_ECD_GABAAR_G	71..252	CDD:349801	52/184 (28%)
		Cys-loop	171..185	CDD:349801	3/13 (23%)