Protein Alignment ort and gabrd

DIOPT Version :10

• Sequence 1: NP_524406.1
• Gene: ort / 45910
• FlyBaseID: FBgn0003011
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: XP_700099.5
• Gene: gabrd / 571422
• ZFINID: ZDB-GENE-081105-170
• Length: 459
• Species: Danio rerio
• Alignment Length: 488
• Identity: 139/488 - (28%)
• Similarity: 210/488 - (43%)
• Gaps: 101/488 - (20%)

  Fly    30 TDI-------LPEDIKRYDKMRPPKKEGQPTIVYFHVTVMGLDSIDENSMTYVADVFFAQTWKDH 87
            |||       |.:.:|.|.:...|...|.|..|...:.|..:|.|.|.:|.|...||..|:|:|.
Zfish    35 TDIEISWLPNLDDLMKGYARNFRPGIGGPPVNVAMAIEVASIDHISEANMEYTMTVFLRQSWRDD 99

  Fly    88 RLRLPENMTQEYRLLEVDWLKNMWRPDSFFKNAKSVTFQTMTIPNHYMWLYKDKTILYMVKLTLK 152
            ||..  |.|.:...|:..::..:|.||:|..||||..|..:|:.|..:.|..|..|||..::|..
Zfish   100 RLSY--NHTNKTLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSSRITST 162

  Fly   153 LSCIMNFAIYPHDTQECKLQMESLSHTTDDLIFQWDPTTPLVVD-ENIELPQVALIRNE-TADCT 215
            ::|.|:...||.|.|||.|.:||..::::|:::.|..:..|:.. :.:||.|..:.... ..:..
Zfish   163 VACDMDLTKYPMDEQECMLDLESYGYSSEDIVYHWSESQKLIHGLDKLELSQFTITDYRFVTEMM 227

  Fly   216 QVYSTGNFTCLEVVFTLKRRLVYYVFNTYIPTCMIVIMSWVSFWIKPEAAPARVTLGVTSLLTLS 280
            ...|.|.|..|.:.|.|:|....|:..:|:|:.::|.||||||||...|.||||:||:|::||::
Zfish   228 NFKSAGRFPRLSLRFQLRRNRGVYIIQSYMPSILLVAMSWVSFWISQSAVPARVSLGITTVLTMT 292

  Fly   281 TQHAKSQSSLPPVSYLKAVDAFMSVCTVFVFMALMEYCLINIVLSDTPIPKPMAYPPKPVAGDGP 345
            |....::||||..|.:||:|.:..:|.||||.||:||...:....         |..|..|....
Zfish   293 TLMVSARSSLPRASAIKALDVYFWICYVFVFAALIEYAFAHYNAD---------YSKKEKAKVKT 348

  Fly   346 KKEGEGAPPGG-------SNSTASKQQATMLPLADEKIEKIEKIFD---------EMTKNRRIVT 394
            .|..|.....|       |.|.|...|..::   ..:..:..:..|         |.|:.|.  .
Zfish   349 NKNAESMVKNGKQAMVLFSLSVAGMNQGLLI---SNRQSRSHRASDAAAAAADPHEETETRS--A 408

  Fly   395 TTRRVVR-----------PPLDADGPWIPRQESRIILTPTIAPPPPPPQPAAPEPELPKPKLTPA 448
            |:||..:           .|:|||
Zfish   409 TSRRAQKESSEEKKCCKCKPIDAD----------------------------------------- 432

  Fly   449 QERLKRAIYIDRSSRVLFPALFASLNGIYWCVF 481
                    .||..:|.:||..||.:|.|||..:
Zfish   433 --------TIDIYARAVFPFTFAVVNVIYWVAY 457

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ort	NP_524406.1	LIC	31..481	CDD:455710	138/485 (28%)
		LGIC_ECD_HisCl	51..235	CDD:349793	58/185 (31%)
		Cys-loop	155..169	CDD:349793	6/13 (46%)
gabrd	XP_700099.5	LIC	45..457	CDD:455710	136/476 (29%)
		LGIC_ECD	64..247	CDD:475126	58/184 (32%)