Protein Alignment ort and gabra6b

DIOPT Version :10

• Sequence 1: NP_524406.1
• Gene: ort / 45910
• FlyBaseID: FBgn0003011
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: XP_002667403.3
• Gene: gabra6b / 559693
• ZFINID: ZDB-GENE-080815-1
• Length: 444
• Species: Danio rerio
• Alignment Length: 470
• Identity: 139/470 - (29%)
• Similarity: 210/470 - (44%)
• Gaps: 84/470 - (17%)

  Fly    29 ITDILPEDIKRYDKMRPPKKEGQPTIVYFHVTVMGLDSIDENSMTYVADVFFAQTWKDHRLRLPE 93
            ||.||...:..||....|...|..|.|...:.|.....:.:..|.|..||||.|||.|.||:. |
Zfish    31 ITRILDRLLDGYDNRLRPGFGGPVTEVKTDIFVTSFGPVSDVEMEYTMDVFFRQTWIDDRLKF-E 94

  Fly    94 NMTQEYRLLEVDWLKNMWRPDSFFKNAKSVTFQTMTIPNHYMWLYKDKTILYMVKLTLKLSCIMN 158
            ...:..||..: .:..:|.||:||:|.|......||.||....:.::.||||.::||:...|.|.
Zfish    95 GPIEILRLNNL-MVSKIWTPDTFFRNGKRSISHNMTTPNKLFRIMQNGTILYTMRLTINAECPMR 158

  Fly   159 FAIYPHDTQECKLQMESLSHTTDDLIFQWDPTTPL----VVDENIELPQVALIRNETADCTQVYS 219
            ...:|.|...|.|:..|.::...::::.| ...||    |..|:..|.|..|| .:|....::.|
Zfish   159 LINFPMDGHSCPLKFGSYAYPMSEIVYTW-KKGPLFSVEVPQESSSLLQYDLI-GQTVSSERLKS 221

  Fly   220 -TGNFTCLEVVFTLKRRLVYYVFNTYIPTCMIVIMSWVSFWIKPEAAPARVTLGVTSLLTLSTQH 283
             ||.:..:.|.|.|:|::.:::..||||..|.||::.|||||..|:.|||...|:|::||::|..
Zfish   222 NTGEYIVMTVYFHLQRKMGFFLIQTYIPCIMTVILAQVSFWIDKESVPARTVFGITTVLTMTTLS 286

  Fly   284 AKSQSSLPPVSYLKAVDAFMSVCTVFVFMALMEYCLINIV--------LSDTPIPKPMAYPPKPV 340
            ..::.|||.|||..|:|.|::||..|||.||:|:..:|..        |....|.:..|
Zfish   287 ISARHSLPKVSYATAMDWFIAVCFAFVFSALIEFAAVNYFSTLQANKELRRANIARAAA------ 345

  Fly   341 AGDGPKKEGEGA----PPGGSNSTASKQQATMLPLADEKIEKIEKIFDEMTKNRRIVTTTRRVVR 401
            |....:.:|||.    .|||                     .::|..:.:::.    :.|.|..|
Zfish   346 AAAAARSDGEGVLNPLDPGG---------------------VLKKRMNSLSQR----SATDRFSR 385

  Fly   402 PPLDADGPWIPRQESRIILTPTIAPPPPPPQPAAPEPELPKPKLTPAQERLKRAIYIDRSSRVLF 466
            |. .:|   ..:|.|.:                            ||...|.....||:.||:||
Zfish   386 PS-QSD---FHQQGSAV----------------------------PANNMLIGTSIIDKYSRILF 418

  Fly   467 PALFASLNGIYWCVF 481
            |..|.:.|.:||.|:
Zfish   419 PLSFGAFNLVYWIVY 433

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ort	NP_524406.1	LIC	31..481	CDD:455710	136/466 (29%)
		LGIC_ECD_HisCl	51..235	CDD:349793	58/188 (31%)
		Cys-loop	155..169	CDD:349793	4/13 (31%)
gabra6b	XP_002667403.3	LIC	33..433	CDD:455710	136/466 (29%)
		LGIC_ECD_GABAAR_A6	41..238	CDD:349840	62/200 (31%)
		Cys-loop	155..169	CDD:349840	4/13 (31%)