Protein Alignment ort and gabrg1

DIOPT Version :10

• Sequence 1: NP_524406.1
• Gene: ort / 45910
• FlyBaseID: FBgn0003011
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: XP_009305483.1
• Gene: gabrg1 / 556202
• ZFINID: ZDB-GENE-141215-66
• Length: 454
• Species: Danio rerio
• Alignment Length: 474
• Identity: 132/474 - (27%)
• Similarity: 212/474 - (44%)
• Gaps: 91/474 - (19%)

  Fly    29 ITDILPEDIKRYDKMRPPKKEGQPTIVYFHVTVMGLDSIDENSMTYVADVFFAQTWKDHRLRLPE 93
            :|.||.:.::.||....|....:||::...|.|..:..:|..:|.|..|:||||||.|.||:.
Zfish    55 VTLILNKLLQGYDNKLRPDIGVRPTVIETAVYVNSIGPVDPINMEYTIDIFFAQTWYDSRLKF-- 117

  Fly    94 NMTQEYRLLEVDWLKNMWRPDSFFKNAKSVTFQTMTIPNHYMWLYKDKTILYMVKLTLKLSCIMN 158
            |.:.:..:|..:.:..:|.||:||:|::......:|.||..:.|:.:..::|.::||:...|.:.
Zfish   118 NSSMKLLMLNSNMVGKIWIPDTFFRNSRKSDAHWITTPNRLLRLWSNGRVMYTLRLTINAECYLK 182

  Fly   159 FAIYPHDTQECKLQMESLSHTTDDLIFQWDPTTPLVVDENI-ELPQVALI--RNETADCTQVYST 220
            ...:|.|...|.|:..|..:..:::.::|...:..|.|:.. .|.|.|.:  || ::|.....|
Zfish   183 LHNFPMDEHSCPLEFSSYGYPKNEIQYRWQRRSVEVADQRYWRLYQFAFVGLRN-SSDVANTQS- 245

  Fly   221 GNFTCLEVVFTLKRRLVYYVFNTYIPTCMIVIMSWVSFWIKPEAAPARVTLGVTSLLTLSTQHAK 285
            |.:..:.:.|.|.||:.|:...||||..|||::|||||||..:|.|||.:||:|::||::|....
Zfish   246 GEYVVMTIFFDLSRRMGYFTIQTYIPCSMIVVLSWVSFWINKDAVPARTSLGITTVLTMTTLSTI 310

  Fly   286 SQSSLPPVSYLKAVDAFMSVCTVFVFMALMEYCLINIVLSDTPIPKPMAYPPKPVAGDGPKKEGE 350
            |:.|||.|||:.|:|.|:|||.:|.|.|||||..::...|:....|              .|...
Zfish   311 SRKSLPKVSYVTAMDLFVSVCFIFTFAALMEYGTLHYFTSNRQNKK--------------TKSSH 361

  Fly   351 GAPPGGSN---STASKQQATMLPLADEKIEKIEKI-----------FDEMTKNRRIVTTTRRVVR 401
            ...|...|   .|:..|...:.|..::.....|.:           ||:.
Zfish   362 AQKPSMVNIRPGTSLLQMNNIAPYHEDDDYAYECLDGKDCTSFFCCFDDC--------------- 411

  Fly   402 PPLDADGPWIPRQESRIILTPTIAPPPPPPQPAAPEPELPKPKLTPAQERLKRAIYIDRSSRVLF 466
                ..|.|   :|:|:.:                                 ....||..||:.|
Zfish   412 ----RSGAW---RENRMHV---------------------------------HVSKIDSYSRIFF 436

  Fly   467 PALFASLNGIYWCVFYEYL 485
            |..|...|.:|| :.|.||
Zfish   437 PTAFGLFNLVYW-IGYLYL 454

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ort	NP_524406.1	LIC	31..481	CDD:455710	128/466 (27%)
		LGIC_ECD_HisCl	51..235	CDD:349793	51/186 (27%)
		Cys-loop	155..169	CDD:349793	3/13 (23%)
gabrg1	XP_009305483.1	LIC	58..451	CDD:455710	128/466 (27%)
		LGIC_ECD_GABAAR_G	79..260	CDD:349801	50/184 (27%)
		Cys-loop	179..193	CDD:349801	3/13 (23%)