DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ort and NtR

DIOPT Version :9

Sequence 1:	NP_524406.1	Gene:	ort / 45910	FlyBaseID:	FBgn0003011	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_651958.2	Gene:	NtR / 43935	FlyBaseID:	FBgn0029147	Length:	585	Species:	Drosophila melanogaster

Alignment Length:	339	Identity:	66/339 - (19%)
Similarity:	130/339 - (38%)	Gaps:	107/339 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    55 VYFHVTVMGLDSIDENSMTYVADVFFAQTWKDHRLRLPENMTQEYRLLEVDWLKNMWRPDSF--- 116
            :.||.....| :.::.|......:.....|:|.||                    :|:|:.|
  Fly   239 ISFHFQTRSL-AYEQTSSLLQTRMHMMMHWRDSRL--------------------VWKPEDFGSL 282

  Fly   117 -------------FKNAKSVTFQTM--TIPNHYMWLYKDKTI-LYMVKLTLKLSCIMNFAIYPHD 165
                         ..|..:...|:|  .:.::.:.:|.:.:| ||...|.|...|:.:...:|.:
  Fly   283 ESFEHPDLRIWKPHMNVLNGALQSMGQVLQSYELMVYANGSITLYAQNLQLASWCVDSARNWPSE 347

  Fly   166 TQECKLQM--------ESLSHTTDDLIFQWDPTTPLVVDENIELP--------QVALIRNETADC 214
            ...|.:::        |:::     ||:. |...|:..:|::..|        .|.|:.|   |.
  Fly   348 RVTCDIELGLNGQEGQENVA-----LIYD-DQRKPIAPNEHVNTPSGWSFTQMSVVLVEN---DS 403

  Fly   215 TQVYS--------TGNFTCLEVVFTLKRRLVYYVFNTYIP--TC-MIVIMSWVSFWIKPEAAPAR 268
            .:.|:        ||:   :.:.|||:|...:|:...|:|  .| |.:|:|:|.      .:..|
  Fly   404 QRRYNPKGMMQKMTGD---VAIEFTLQRNRSFYMTVFYLPLIACQMFLILSFVL------RSTRR 459

  Fly   269 VTLGVTSLLTLS------TQHAKSQSSLPPVSYLKAVDAFMSVCTVFVFMALMEYCLINIVLSDT 327
            .:|.:.:||..:      |::| |...:||:     :.|:..:.....:..::..|:|.:.|
  Fly   460 SSLILIALLIAAWGLMYMTRYA-SPHYVPPM-----MTAYKVIMMTTTYCYILHICIIWLDL--- 515

  Fly   328 PIPKPMAYPPKPVA 341
                   |||:..|
  Fly   516 -------YPPRSKA 522

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ort	NP_524406.1	LIC	31..481	CDD:273305	66/339 (19%)
		Neur_chan_LBD	38..235	CDD:280998	40/222 (18%)
		Neur_chan_memb	243..>334	CDD:280999	20/99 (20%)
NtR	NP_651958.2	Methyltransf_FA	90..191	CDD:289052
NtR	NP_651958.2	Neur_chan_LBD	212..429	CDD:280998	40/222 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR18945
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100