Protein Alignment ort and pHCl-2

DIOPT Version :10

• Sequence 1: NP_524406.1
• Gene: ort / 45910
• FlyBaseID: FBgn0003011
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: NP_651861.1
• Gene: pHCl-2 / 43703
• FlyBaseID: FBgn0039840
• Length: 526
• Species: Drosophila melanogaster
• Alignment Length: 483
• Identity: 126/483 - (26%)
• Similarity: 220/483 - (45%)
• Gaps: 51/483 - (10%)

  Fly    25 QSLAITDILPEDIK--RYDKMRPP---KKEGQ--PTIVY--FHVTVMGLDSIDENSMTYVADVFF 80
            :|:|:.::|.....  |||:|.||   .|:|:  |..:|  |::.||  .::|.:.:.:......
  Fly    68 ESMALMELLTRLTAPCRYDRMVPPVVHNKDGEEVPMDIYARFYIYVM--KNLDSSDLQFTVQGLL 130

  Fly    81 AQTWKDHRLRLPENMTQEYRLL--EVDWLKNMWRPDSFFKNAKSVTFQTMTIPNHYMWLYKDKTI 143
            ...:.|.||.....:....:.:  |.:..|.:|.|..|..|.::.|....:..:....:|.:.|:
  Fly   131 QLRYLDPRLAFSSYLPNRRQPIMGESELKKMLWVPHIFLTNEQASTVLGTSAKDELTSIYPNGTV 195

  Fly   144 LYMVKLTLKLSCIMNFAIYPHDTQECKLQMESLSHTTDDLIFQWDPTTPLVVDENIELPQVALIR 208
            |...:|...|.|.|||..:|.|.|:||..:||..:.|..:...|:...|:..|:.::|.:..||.
  Fly   196 LTSTRLQATLYCWMNFQKFPFDEQKCKTTLESWMYNTTLVQLHWETDNPVSFDKQLQLTEYNLIG 260

  Fly   209 NETADCTQVYS---------TGNFTCLEVVFTLKRRLVYYVFNTYIPTCMIVIMSWVSFWIKPEA 264
            :...:..:|.:         .||::.:.....|.|.:.|||.:.::|:.|||.:||||||::.:.
  Fly   261 SLYNESIRVSNESYMSHGSLEGNYSIISFTVLLTREVGYYVIDYFLPSIMIVTISWVSFWLQADQ 325

  Fly   265 APARVTLGVTSLLTLSTQHAKSQSSLPPVSYLKAVDAFMSVCTVFVFMALMEYCLINIVL---SD 326
            .|||.|||.|:||:..|.....:::|..|||:...:.:..|||:|:|.:|:|:..:|.:.   :|
  Fly   326 TPARTTLGCTTLLSFITLSLSQENNLMKVSYVTMSEVWFLVCTIFIFGSLVEFAFVNTIWRRNND 390

  Fly   327 TPIPK-PMAYPPKPVAGDGPKKEGEGAPPGGSNSTASKQQATMLPLADEKIEKIEKIFDEMTKNR 390
            ..:.| ...|..|.......||...    .|...|.|    ||..::...::|      ....|.
  Fly   391 LQLKKRTTKYIVKSTFVPHLKKHRR----HGYRRTDS----TMSTMSTTSMDK------TCGPNN 441

  Fly   391 RIVTTTRRVVRPPLDADGPWIPRQESRIILTPTIAPPPPPPQPAAPEPELPKPKLTPAQERLKR- 454
            .::|     :..|:...|. :.|::|.|.|.............::.|    ||..|.|....|.
  Fly   442 TVIT-----IETPIIIGGS-LSREDSAISLDEQDETSTSESSDSSKE----KPAQTFATMTPKEV 496

  Fly   455 AIYIDRSSRVLFPALFASLNGIYWCVFY 482
            :::|||..|.:||..|...|.::|.:.|
  Fly   497 SLWIDRKMRFVFPLSFIVFNALFWTLVY 524

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ort	NP_524406.1	LIC	31..481	CDD:455710	123/474 (26%)
		LGIC_ECD_HisCl	51..235	CDD:349793	43/198 (22%)
		Cys-loop	155..169	CDD:349793	7/13 (54%)
pHCl-2	NP_651861.1	LIC	46..522	CDD:455710	125/479 (26%)