Protein Alignment ort and nAChRalpha1

DIOPT Version :9

• Sequence 1: NP_524406.1
• Gene: ort / 45910
• FlyBaseID: FBgn0003011
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: NP_001262916.1
• Gene: nAChRalpha1 / 42918
• FlyBaseID: FBgn0000036
• Length: 597
• Species: Drosophila melanogaster
• Alignment Length: 427
• Identity: 85/427 - (19%)
• Similarity: 149/427 - (34%)
• Gaps: 140/427 - (32%)

  Fly     7 ILVICTICMKHYAKGEFQQSLAITDI--LPED-IKRYDKM-RPPKKEGQPTIVYFHVTVMGLDSI 67
            :|........|:|.|    .||..|.  |.:| :..|::: ||.........|...:.:..|..:
  Fly     4 VLFAAVFIALHFATG----GLANPDAKRLYDDLLSNYNRLIRPVGNNSDRLTVKMGLRLSQLIDV 64

  Fly    68 DENSMTYVADVFFAQTWKDHRLRLPENMTQEYRLLEVDWLKNMWRPDSFFKNAKSVTFQTMTIPN 132
            :..:.....:|:..|.|.|::|:                    |.||.:      ....|:.:|:
  Fly    65 NLKNQIMTTNVWVEQEWNDYKLK--------------------WNPDDY------GGVDTLHVPS 103

  Fly   133 HYMWLYKDKTILY-----------MVKLTL--------------KLSCIMNFAIYPHDTQECKLQ 172
            .::||  ...:||           |.|..|              |..|.::...:|.|.|.|.::
  Fly   104 EHIWL--PDIVLYNNADGNYEVTIMTKAILHHTGKVVWKPPAIYKSFCEIDVEYFPFDEQTCFMK 166

  Fly   173 MES------------LSHTTDD-------------LIFQWDPTTPLVVDENIELPQVALIRNETA 212
            ..|            |..|.|.             :..:||            :.:|..:|||
  Fly   167 FGSWTYDGYMVDLRHLKQTADSDNIEVGIDLQDYYISVEWD------------IMRVPAVRNE-- 217

  Fly   213 DCTQVYSTGNFTCLEVVF--TLKRRLVYYVFNTYIPTCMIVIMSWVSFWIKPEAAPARVTLGVTS 275
               :.||......|::||  ||:|:.::|..|..||...|..:|.:.|:: |..:..:::|.::.
  Fly   218 ---KFYSCCEEPYLDIVFNLTLRRKTLFYTVNLIIPCVGISFLSVLVFYL-PSDSGEKISLCISI 278

  Fly   276 LLTLSTQHAKSQSSLPPVS--------YLKAVDAFMSVCTVFVFMALMEYCLINIVLSDTPIPKP 332
            ||:|:.........:||.|        ||           :|..|.:....::.|.:.:.....|
  Fly   279 LLSLTVFFLLLAEIIPPTSLTVPLLGKYL-----------LFTMMLVTLSVVVTIAVLNVNFRSP 332

  Fly   333 MAYP-------------PKPVAGDGPKKE--GEGAPP 354
            :.:.             ||.:..:.||||  .|..||
  Fly   333 VTHRMAPWVQRLFIQILPKLLCIERPKKEEPEEDQPP 369

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ort	NP_524406.1	LIC	31..481	CDD:273305	79/403 (20%)
		Neur_chan_LBD	38..235	CDD:280998	45/249 (18%)
		Neur_chan_memb	243..>334	CDD:280999	19/98 (19%)
nAChRalpha1	NP_001262916.1	Neur_chan_LBD	25..240	CDD:280998	48/259 (19%)
		LIC	27..530	CDD:273305	78/400 (20%)
		Neur_chan_memb	247..530	CDD:280999	28/135 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR18945
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100