Protein Alignment ort and Grd

DIOPT Version :9

• Sequence 1: NP_524406.1
• Gene: ort / 45910
• FlyBaseID: FBgn0003011
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: NP_524131.1
• Gene: Grd / 39984
• FlyBaseID: FBgn0001134
• Length: 686
• Species: Drosophila melanogaster
• Alignment Length: 585
• Identity: 144/585 - (24%)
• Similarity: 235/585 - (40%)
• Gaps: 150/585 - (25%)

  Fly    29 ITDILPEDIKRYDKMRPPKKEGQPTIVYFHVTVMGLDSIDENSMTYVADVFFAQTWKDHRLRLPE 93
            |:::|...::.||....|...|.|..:...:.|..:..|.|..|||..|.:|.|:|.|.||..
  Fly   109 ISELLDNLLRGYDNSIRPDFGGPPATIEVDIMVRSMGPISEVDMTYSMDCYFRQSWVDKRLAF-- 171

  Fly    94 NMTQEYRLLEVDWLKNMWRPDSFFKNAKSVTFQTMTIPNHYMWLYKDKTILYMVKLTLKLSCIMN 158
            ...|:...|.|..|..:|:||::|.|.|.....|:|.||.::.:|::..:||..:||:|..|.||
  Fly   172 EGAQDTLALSVSMLARIWKPDTYFYNGKQSYLHTITTPNKFVRIYQNGRVLYSSRLTIKAGCPMN 236

  Fly   159 FAIYPHDTQECKLQMESLSHTTDDLIFQWD-PTTPLVVDENIELPQVALIRNETADCTQV----- 217
            .|.:|.|.|:|.|:..|..:||.|:|::|: ...|:.:.|:::|.|..|:.....:.|.:
  Fly   237 LADFPMDIQKCPLKFGSFGYTTSDVIYRWNKERPPVAIAEDMKLSQFDLVDCPAGNLTDIVYKAA 301

  Fly   218 ----------------------------------------------YSTG--------------- 221
                                                          :.||
  Fly   302 APRPQRRPFNNKDPPRPTSKVMTTFAGPAAKNQHVRGTGLKLDKGAFGTGRDATGGSGSTTGLSG 366

  Fly   222 ----------NFTCLEVVFTLKRRLVYYVFNTYIPTCMIVIMSWVSFWIKPEAAPARVTLGVTSL 276
                      .::.|.|.|.|:|.:..::...|.|.|::|::||||||:..||...||:||:|::
  Fly   367 TITLETNHPSEYSMLMVNFHLQRHMGNFLIQVYGPCCLLVVLSWVSFWLNREATADRVSLGITTV 431

  Fly   277 LTLSTQHAKSQSSLPPVSYLKAVDAFMSVCTVFVFMALMEYCLINIVLSDTPIPKPMAYPPKPVA 341
            ||::....::::.||.|||..|:|.|:.:...|:|..::::.:::             |..|..:
  Fly   432 LTMTFLGLEARTDLPKVSYPTALDFFVFLSFGFIFATILQFAVVH-------------YYTKYGS 483

  Fly   342 G---------DGPKKEGEGAPPGGS--NSTASK--------QQATMLPLADEKIEKIEKIFDEMT 387
            |         |....|.|..|....  .||.||        ..|..:|....::..:.. .:...
  Fly   484 GECYFIIEELDSESGESETEPLTSDFRGSTESKIYEVIPLSMCAISMPPPPTRLGMLTS-RNRRP 547

  Fly   388 KNRR----------IVTTTRRVVRPPLDADGPWIPRQ-ESRIILTPTIAPPPPPPQPAAPEPELP 441
            :|||          :....||...|..|:|......| :.|....||.:......|.||....:.
  Fly   548 RNRRHGLWSMKLLGLFDWRRRRKPPRADSDEDEDDEQTQLRANEAPTTSAAAAAAQAAAQAARIS 612

  Fly   442 KP---------------------KLTPAQERLKRAIYIDRSSRVLFPALFASLNGIYWCVFYEYL 485
            .|                     |.||....:.:   |||:||::||.||..:|..||   |.||
  Fly   613 PPTGGRRRMSYYRREEMEARRKGKRTPQYNSVSK---IDRASRIVFPLLFILINVFYW---YGYL 671

  Fly   486  485
              Fly   672  671

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ort	NP_524406.1	LIC	31..481	CDD:273305	140/577 (24%)
		Neur_chan_LBD	38..235	CDD:280998	65/273 (24%)
		Neur_chan_memb	243..>334	CDD:280999	29/90 (32%)
Grd	NP_524131.1	Neur_chan_LBD	110..326	CDD:280998	60/217 (28%)
		LIC	111..670	CDD:273305	141/580 (24%)
		Neur_chan_memb	398..667	CDD:280999	71/285 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR18945
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.910