Protein Alignment ort and SecCl

DIOPT Version :10

• Sequence 1: NP_524406.1
• Gene: ort / 45910
• FlyBaseID: FBgn0003011
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: NP_648984.2
• Gene: SecCl / 39949
• FlyBaseID: FBgn0036727
• Length: 509
• Species: Drosophila melanogaster
• Alignment Length: 551
• Identity: 125/551 - (22%)
• Similarity: 222/551 - (40%)
• Gaps: 122/551 - (22%)

  Fly     2 VFQIIILVICTI------------CMKHYAKGEFQQSLAITDILPEDIKRYDKMRPP---KKEGQ 51
            :|.|.::::.:|            |......|..||:..|..:  ..:.|||::..|   ..:|:
  Fly     9 IFWITLILVLSIWTSVGVKAEEEECPSMADAGSLQQTQLIQRL--THVCRYDRLERPFEYDSDGK 71

  Fly    52 --PTIVYFHVTVMGLDSIDENSMTYVADVFFAQTWKDHRL-----RLPENMTQEYRLLEVDWLKN 109
              |.:|...:.|..|.:::.:.:.:.........::|.||     ...:|:..:..|.|     .
  Fly    72 RLPIVVKTRIYVYFLQNLNSDLLQFKMHALLQLRFQDKRLAYKAFNRSDNILGQKHLSE-----R 131

  Fly   110 MWRPDSFFKNAKSVTFQTMTIPNHYMWLYKDKTILYMVKLTLKLSCIMNFAIYPHDTQECKLQME 174
            :|.|..||.|.:..:.......:....|..:..::...::...|.|.|||..:|.|.|.|...:|
  Fly   132 LWLPHIFFANERESSILGTDEKDVLTSLSPEGNVIISTRMQASLYCWMNFQKFPFDQQFCSTVLE 196

  Fly   175 SLSHTTDDLIFQWDPTTPLVVDENIELPQ---------VALIRNETADCTQVYSTGNFTCLEVVF 230
            |..:.|.|||.:|:|.||:..|..:.|.:         ..:::::..:.......||::.|....
  Fly   197 SWMYNTSDLILEWEPHTPISFDPEMRLTEYNMAQFWHNTTIVQSDGDNLRHGAFAGNYSSLSFTV 261

  Fly   231 TLKRRLVYYVFNTYIPTCMIVIMSWVSFWIKPEAAPARVTLGVTSLLTLSTQHAKSQSSLPPVSY 295
            .|||.:.:|:.:.|:|:.|||.:||||||::.:|:|.|:.||.:::|:..|..:....:||.|||
  Fly   262 NLKREIGFYLLDYYLPSMMIVAISWVSFWLQADASPPRIMLGTSTMLSFITLSSSQSKNLPKVSY 326

  Fly   296 LKAVDAFMSVCTVFVFMALMEYCLIN-----------------IVLSDTPIPKPMAYPPKPVAGD 343
            :|..:.:...||.|:|.:|:|:..:|                 .::..|..|:|..   :.:.|.
  Fly   327 IKVSEVWFLGCTFFIFGSLVEFAFVNTIWRRKENIELKKVNSKYIIKSTLTPRPAR---RQIGGS 388

  Fly   344 --------------------GPKKEGEGAPPGGSNSTASKQQATMLPLADEKIEKIE--KIFDEM 386
                                ...:.|.|....|.|:..:..  ..||:...:..:.:  .|....
  Fly   389 LSNESRARSCSSLDNIVSSTESVRNGNGTVNQGFNNYLTVH--PNLPIIRTECAEADTVSICSAR 451

  Fly   387 TKNRRIVTTTRRVVRPPLDADGPWIPRQESRIILTPTIAPPPPPPQPAAPEPELPKPKLTPAQER 451
            |.|..||         .:|.|....|         ||..                  .:||.:
  Fly   452 TNNDHIV---------DVDKDKKDTP---------PTFT------------------TMTPQE-- 478

  Fly   452 LKRAIYIDRSSRVLFPALFASLNGIYWCVFY 482
              .|::|||.||.||||:|.:.|.:||...|
  Fly   479 --IAMWIDRRSRFLFPAMFLAFNALYWTFVY 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ort	NP_524406.1	LIC	31..481	CDD:455710	116/507 (23%)
		LGIC_ECD_HisCl	51..235	CDD:349793	42/199 (21%)
		Cys-loop	155..169	CDD:349793	7/13 (54%)
SecCl	NP_648984.2	LIC	43..505	CDD:455710	119/513 (23%)