Protein Alignment ort and pHCl-1

DIOPT Version :9

• Sequence 1: NP_524406.1
• Gene: ort / 45910
• FlyBaseID: FBgn0003011
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: NP_001261898.1
• Gene: pHCl-1 / 39730
• FlyBaseID: FBgn0264908
• Length: 978
• Species: Drosophila melanogaster
• Alignment Length: 696
• Identity: 157/696 - (22%)
• Similarity: 253/696 - (36%)
• Gaps: 233/696 - (33%)

  Fly     6 IILVICTICM---------------KHYAKG----EFQQSLA---ITDILPEDIKRYDK------ 42
            ::|::|.:..               ||...|    :|.:|.:   |.|:|.|. |||||
  Fly   295 VLLMLCYLTTASTAAATQSETGALDKHPIHGIDWSKFDESSSDKEILDLLLEK-KRYDKRLLPPV 358

  Fly    43 -------------------MRPPKKEGQPTIVYFHVTVMGLDSIDENSMTYVADVFFAQTWKDHR 88
                               .|.|...|..| |..:|.::.|.|.||:|:.|..:....|.|.|.|
  Fly   359 NDEDFCCGLQSPDMATNQNARRPHNRGTLT-VNVNVLLLSLASPDESSLKYEVEFLLNQQWNDPR 422

  Fly    89 LRLPENMTQEYRLLEVDWLKNMWRPDSFFKNAKSVTFQTMTIPNHY-MWLYKDKTILYMVKLTLK 152
            |:.......:: |..:....::|.||::|  .....|:...||.|: :.::::.||.|.::..|.
  Fly   423 LQYGNKSHYDF-LNALHHHDSIWTPDTYF--IMHGDFKDPIIPMHFALRIFRNGTITYAMRRHLI 484

  Fly   153 LSCIMNFAIYPHDTQECKLQMESLSHTTDDLIFQW--DPTTPLVVDENIELPQVALIRNETADCT 215
            |||..:..|:|.|..:|...|||:|:....:.:.|  |..| |....::......||:|:|..|.
  Fly   485 LSCQGSLHIFPFDDPKCSFSMESISYEEAQIKYVWKNDEDT-LRKSPSLTTLNAYLIKNQTTACD 548

  Fly   216 QVYSTGNFTCLEVVFTLKRRLVYYVFNTYIPTCMIVIMSWVSFWIKPEAAPARVTLGVTSLLTLS 280
            |....||::||:|..|..|...||....:||..::|..|:::||::..|.||||.:|||::|...
  Fly   549 QNSWRGNYSCLQVELTFTRDRAYYFTTVFIPGIILVTSSFITFWLEWNAVPARVMIGVTTMLNFF 613

  Fly   281 TQHAKSQSSLPPVSYLKAVDAFMSVCTVFVFMALMEYCLINIVLSDTPIPKPMAYPP-------- 337
            |.....:|:||.||.|.|::.:..||..|::.:|:|:..:|.|....|:.. :.|.|
  Fly   614 TTSNGFRSTLPVVSNLTAMNVWDGVCMCFIYASLLEFVCVNYVGRKRPLHN-VVYRPGENPVTQR 677

  Fly   338 -------------KPVA------------GDGPKKEG---------------------------- 349
                         .|:|            |..|...|
  Fly   678 LPAVLSRIGVILASPLASAAATPAMSMMGGATPMSSGTPAASSSVATPGTPRITDPEEFFGGGMR 742

  Fly   350 -------------------------------------EGAP-------PGGSNSTASKQQATMLP 370
                                                 .|.|       ||||.|..:   :|.:.
  Fly   743 WQEAHGGIIGAAVQNLRARSIKRKAARSPSTSISPHPSGRPTEHIYEEPGGSTSGVT---STKVK 804

  Fly   371 LADEKIEKIEKIFDEMTKNRRIVTTT--RRVVRPPLDADGPWIPRQESRII----LTP-TIAPPP 428
            ..||..|:..:..:..||.||.|.|:  ..|||...:.|    |..|.:.|    :|. .::.|.
  Fly   805 FKDELKEEQPEEAESSTKLRRSVATSTPALVVRIEAEID----PEAEDKPIQDMEMTERQLSLPL 865

  Fly   429 PPPQPAAPEPELP---------KPKLTPAQER--------------------------------- 451
            .||:..|.....|         ..:.||.::|
  Fly   866 KPPRRKASRSNSPASVYSDAFENVEATPGEKRQNAGAPNEIVACTTCGGSNSPCTHSANNGCATE 930

  Fly   452 --------------LKRAIYIDRSSRVLFPALFASLNGIYWCVFYE 483
                          ::.|..||..:|:.||..:| :..|::.|.|:
  Fly   931 TCFVQVRKKEPPHPIRVAKTIDVIARITFPTAYA-IFLIFFFVHYK 975

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ort	NP_524406.1	LIC	31..481	CDD:273305	147/645 (23%)
		Neur_chan_LBD	38..235	CDD:280998	62/224 (28%)
		Neur_chan_memb	243..>334	CDD:280999	31/90 (34%)
pHCl-1	NP_001261898.1	Neur_chan_LBD	338..566	CDD:280998	66/233 (28%)
		Neur_chan_memb	578..>682	CDD:280999	33/104 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S5256
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D614790at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR18945
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.970