Protein Alignment ort and nAChRalpha6

DIOPT Version :10

• Sequence 1: NP_524406.1
• Gene: ort / 45910
• FlyBaseID: FBgn0003011
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: NP_995675.1
• Gene: nAChRalpha6 / 34304
• FlyBaseID: FBgn0032151
• Length: 523
• Species: Drosophila melanogaster
• Alignment Length: 352
• Identity: 78/352 - (22%)
• Similarity: 148/352 - (42%)
• Gaps: 70/352 - (19%)

  Fly     5 IIILVICTICMKHYAKGEFQQSLAITDILPEDIKRYDKM-RPPKKEGQPTIVYFHVTVMGLDSID 68
            :.:|:|....:|...:|..::.|     |...:..|:.: ||...|.:|..|.|.:|:..:..:|
  Fly    11 LFVLLIFLAIIKESCQGPHEKRL-----LNHLLSTYNTLERPVANESEPLEVKFGLTLQQIIDVD 70

  Fly    69 ENSMTYVADVFFAQTWKDHRLRLPENMTQEYRLLEVDWLKNMWRPDSFFKNAKSV----TFQTMT 129
            |.:.....:.:....|.|:.||..|......:.|.:...| :|:||....|:...    |:.|..
  Fly    71 EKNQILTTNAWLNLEWNDYNLRWNETEYGGVKDLRITPNK-LWKPDVLMYNSADEGFDGTYHTNI 134

  Fly   130 IPNHYMWLYKDKTILYMVKLTLKLSCIMNFAIYPHDTQECKLQMESLSHTTDDLIFQWDPTTPLV 194
            :..|      :.:.||:.....|.:|.::...:|.|.|.|:::..|.::
  Fly   135 VVKH------NGSCLYVPPGIFKSTCKIDITWFPFDDQHCEMKFGSWTY---------------- 177

  Fly   195 VDENIELPQVALIRN--ETADCTQVYSTGN--------------FTC-----LEVVFT--LKRRL 236
             |.|    |:.|:.|  :..|.:...:.|.              :.|     :::.||  ::||.
  Fly   178 -DGN----QLDLVLNSEDGGDLSDFITNGEWYLLAMPGKKNTIVYACCPEPYVDITFTIQIRRRT 237

  Fly   237 VYYVFNTYIPTCMIVIMSWVSFWIKPEAAPARVTLGVTSLLTLSTQHAKSQSSLPPVSYLKAVDA 301
            :||.||..:|..:|..|:.:.|.:.|::. .::|||||.||:|:........|:|..|     ||
  Fly   238 LYYFFNLIVPCVLISSMALLGFTLPPDSG-EKLTLGVTILLSLTVFLNLVAESMPTTS-----DA 296

  Fly   302 FMSVCTVFVFMALMEYCLINIVLSDTP 328
             :.:..|.:.::|..:  :|:|....|
  Fly   297 -VPLIGVTILLSLTVF--LNLVAETLP 320

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ort	NP_524406.1	LIC	31..481	CDD:455710	73/326 (22%)
		LGIC_ECD_HisCl	51..235	CDD:349793	39/210 (19%)
		Cys-loop	155..169	CDD:349793	4/13 (31%)
nAChRalpha6	NP_995675.1	LIC	11..517	CDD:455710	78/352 (22%)
		LGIC_ECD_nAChR	55..236	CDD:349798	38/208 (18%)
		Cys-loop	154..168	CDD:349798	4/13 (31%)