Protein Alignment ort and gabrb2a

DIOPT Version :10

• Sequence 1: NP_524406.1
• Gene: ort / 45910
• FlyBaseID: FBgn0003011
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: NP_001019558.2
• Gene: gabrb2a / 336252
• ZFINID: ZDB-GENE-030131-8196
• Length: 519
• Species: Danio rerio
• Alignment Length: 556
• Identity: 151/556 - (27%)
• Similarity: 252/556 - (45%)
• Gaps: 124/556 - (22%)

  Fly     2 VFQIIILVICTICMKHYAKGEFQQSL-------AITDILPEDIKRYDKMRPPKKEGQPTIVYFHV 59
            :|.:..|::...|         .||:       .:.|.:...:|.||....|...|.|..|..::
Zfish    10 IFLLCPLIVAVAC---------AQSIRDPSNMPVVKDTVDRLMKGYDIRLRPDFGGAPVAVGMNI 65

  Fly    60 TVMGLDSIDENSMTYVADVFFAQTWKDHRL---RLPENMTQEYRLLEVDWLKNMWRPDSFFKNAK 121
            .:..:|.:.|.:|.|...::|.|.|:|.||   .:|.|:|.:.|:.:     .:|.||::|.|.|
Zfish    66 DIASIDMVSEVNMDYTLTMYFQQAWRDKRLSYSEIPLNLTLDNRVAD-----QLWVPDTYFLNDK 125

  Fly   122 SVTFQTMTIPNHYMWLYKDKTILYMVKLTLKLSCIMNFAIYPHDTQECKLQMESLSHTTDDLIFQ 186
            ......:|:.|..:.|:.|.|:||.:::|...:|:|:...||.|.|.|.|::||..:||||:.|.
Zfish   126 KSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFY 190

  Fly   187 W---DPTTPLVVDENIELPQVALIRNETADCTQVYSTGNFTCLEVVFTLKRRLVYYVFNTYIPTC 248
            |   |.....|  |.|||||.:::..:......|:|||::..|.:.|.|||.:.|::..||:|:.
Zfish   191 WRGGDGAVSGV--ERIELPQFSIVDYKLISKNVVFSTGSYPRLSLSFKLKRNIGYFILQTYMPSI 253

  Fly   249 MIVIMSWVSFWIKPEAAPARVTLGVTSLLTLSTQHAKSQSSLPPVSYLKAVDAFMSVCTVFVFMA 313
            :|.|:|||||||..:|:.|||.||:|::||::|.:...:.:||.:.|:||:|.::..|.||||:|
Zfish   254 LITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLA 318

  Fly   314 LMEYCLINIVLSDTPIPKPMAYPPKPVAGDGPKKEGEGAPPGGSNSTASKQQATMLP---LADEK 375
            |:||..:|.:.                .|.||:::.:.|...   :||:.::....|   |....
Zfish   319 LLEYAFVNYIF----------------FGRGPQRQKKAAEKA---ATANNEKLRPDPNKWLVGSV 364

  Fly   376 IEKIEKIFDEMTKNRRIVTTTRRVVRPPLDA-DGPWIP---------RQESRIILTP-----TIA 425
            :::.:.::..| |.|.|            |. |..|.|         ..:.|:.:||     |..
Zfish   365 VQRDDALYARM-KQREI------------DGYDSMWDPIFAEDAALGLGDQRLKMTPDDIRLTTV 416

  Fly   426 PPPPPPQPAAPEPELPKPK-------------------------------LTPAQERLKRAI--- 456
            .......|:.....|..|:                               .|..:.||:|..
Zfish   417 EMKNEMGPSDLSRGLGDPRSTMLAYDSSTLQYRRAAMARQNYGHSALERHATQKKSRLRRRASQL 481

  Fly   457 -----------YIDRSSRVLFPALFASLNGIYWCVF 481
                       .||:.||::||.||:..|.:||..:
Zfish   482 KVNIPDLSDVNSIDKWSRMIFPTLFSFFNIVYWLYY 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ort	NP_524406.1	LIC	31..481	CDD:455710	146/518 (28%)
		LGIC_ECD_HisCl	51..235	CDD:349793	62/189 (33%)
		Cys-loop	155..169	CDD:349793	6/13 (46%)
gabrb2a	NP_001019558.2	LIC	7..517	CDD:273305	151/554 (27%)