Protein Alignment ort and nAChRalpha7

DIOPT Version :9

• Sequence 1: NP_524406.1
• Gene: ort / 45910
• FlyBaseID: FBgn0003011
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: NP_001162795.1
• Gene: nAChRalpha7 / 32928
• FlyBaseID: FBgn0086778
• Length: 564
• Species: Drosophila melanogaster
• Alignment Length: 558
• Identity: 114/558 - (20%)
• Similarity: 209/558 - (37%)
• Gaps: 152/558 - (27%)

  Fly     1 MVFQIIILVICTICMKHYAKGEFQQSL--AITDILPEDIKRYDKM-RPPKKEGQPTIVYFHVTVM 62
            :|:.:.:|::...|    |.|..::.|  |:.|       .|:.: ||...|..|..:.|.:|:|
  Fly    42 LVYGLGLLIMIPAC----AAGPHEKRLLHALLD-------NYNSLERPVVNESDPLQLSFGLTLM 95

  Fly    63 GLDSIDENSMTYVADVFFAQTWKDHRLRLPENMTQEYRLLEVDWLKNMWRPDSFFKNAKSVTFQT 127
            .:..:||.:...:.:::....|.|..||...:.....|.|.:. ...:|:||....|:....|..
  Fly    96 QIIDVDEKNQLLITNIWLKLEWNDMNLRWNSSEFGGVRDLRIP-PHRLWKPDVLMYNSADEGFDG 159

  Fly   128 MTIPNHYMWLYKDKTILYMVKLTLKLSCIMNFAIYPHDTQECKLQMESLSHTTDDLIFQWD---- 188
            ....|  :.:..:.:.||:.....|.:|.::...:|.|.|.|:::..|.::..    ||.|
  Fly   160 TYATN--VVVRNNGSCLYVPPGIFKSTCKIDITWFPFDDQRCEMKFGSWTYDG----FQLDLQLQ 218

  Fly   189 -----PTTPLVVDENIELPQVALIRNETADCTQVYSTGNFTC-----LEVVFT--LKRRLVYYVF 241
                 ..:..:.:...:|..|...|||      :|    :.|     :::.|.  ::|:.:||.|
  Fly   219 DEAGGDISSFITNGEWDLLGVPGKRNE------IY----YNCCPEPYIDITFAILIRRKTLYYFF 273

  Fly   242 NTYIPTCMIVIMSWVSFWIKPEAAPARVTLGVTSLLTLSTQHAKSQSSLPPVS--------YLKA 298
            |..:|..:|..|:.:.|.:.|::. .:::||||.||:|:........::|..|        |...
  Fly   274 NLIVPCVLIASMALLGFTLPPDSG-EKLSLGVTILLSLTVFLNMVAETMPATSDAVPLLGTYFNC 337

  Fly   299 VDAFMSVCTVFVFMALMEY-----------------------CLINIVLSDTPIPKPMAY--PPK 338
            : .||...:|...:.::.|                       |::.:     ..|..:.|  ||
  Fly   338 I-MFMVASSVVSTILILNYHHRNPDTHEMSEWIRVIFLYWLPCILRM-----QRPGQVGYECPP- 395

  Fly   339 PVAGDGPKKEGEGAPPGGSNSTAS---KQQATMLPLADEK----IEKIEKIFDEMTKNRRIVTTT 396
                          ||..|:|:||   |||...:.|.:..    :..:..|.|:...|.|..:.|
  Fly   396 --------------PPSSSSSSASGEKKQQIQNVELKERSSKSLLANVLDIDDDFRCNHRCASAT 446

  Fly   397 --------RRVVRPPLDAD----GPWIPRQESRI-------ILTPTIAPPPPPPQPAAPEPELPK 442
                    |.:.|...|..    ||..|..:.|:       .||.:          |..|..|..
  Fly   447 LPHQPTYYRTMYRQGDDGSVGPVGPAGPVVDGRLHEAISHTCLTSS----------AEYELALIL 501

  Fly   443 PKLTPAQERLKR--------------AIYIDRSSRVLF 466
            .:|....|:||:              |:.:||...::|
  Fly   502 KELRWITEQLKKEDETSDITRDWKFAAMVVDRLCLIIF 539

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ort	NP_524406.1	LIC	31..481	CDD:273305	107/526 (20%)
		Neur_chan_LBD	38..235	CDD:280998	42/213 (20%)
		Neur_chan_memb	243..>334	CDD:280999	21/121 (17%)
nAChRalpha7	NP_001162795.1	LIC	59..548	CDD:273305	109/537 (20%)
		Neur_chan_LBD	61..268	CDD:280998	46/230 (20%)
		Neur_chan_memb	275..552	CDD:280999	59/297 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR18945
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100