Protein Alignment ort and nAChRalpha3

DIOPT Version :9

• Sequence 1: NP_524406.1
• Gene: ort / 45910
• FlyBaseID: FBgn0003011
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: NP_001285015.1
• Gene: nAChRalpha3 / 31767
• FlyBaseID: FBgn0015519
• Length: 795
• Species: Drosophila melanogaster
• Alignment Length: 504
• Identity: 100/504 - (19%)
• Similarity: 176/504 - (34%)
• Gaps: 175/504 - (34%)

  Fly     3 FQIIILVICTICMKHYAKGEFQQSLAITDI--LPED-IKRYDKM-RPPKKEGQPTIVYFHVTVMG 63
            ||:.|.:|..:..       ...|.|..|.  |.:| :..|:|: ||.........|...:.:..
  Fly     4 FQVTIDMILVLSF-------ISSSTANPDAKRLYDDLLSNYNKLVRPVVNVTDALTVRIKLKLSQ 61

  Fly    64 LDSIDENSMTYVADVFFAQTWKDHRLRLPENMTQEYRLLEVDWLKNMWRPDSFFKNAKSVTFQ-- 126
            |..::..:.....:::..|:|.|::|:..........:|.|. ..::||||....|.....|:
  Fly    62 LIDVNLKNQIMTTNLWVEQSWYDYKLKWEPKEYGGVEMLHVP-SDHIWRPDIVLYNNADGNFEVT 125

  Fly   127 -----TMTIPNHYMW----LYKDKTILYMVKLTLKLSCIMNFAIYPHDTQECKLQMES------- 175
                 |:.......|    :||.             ||.::...:|.|.|.|.::..|
  Fly   126 LATKATLNYTGRVEWRPPAIYKS-------------SCEIDVEYFPFDEQTCVMKFGSWTYDGFQ 177

  Fly   176 --LSHTTDDLIFQWDPTTPLVVDENIELP-----------QVALIRNETADCTQVYSTGNFTC-- 225
              |.| .|:|    :.|.  ||:..::|.           :|..:|||..          :||
  Fly   178 VDLRH-IDEL----NGTN--VVEVGVDLSEFYTSVEWDILEVPAVRNEKF----------YTCCD 225

  Fly   226 ---LEVVF--TLKRRLVYYVFNTYIPTCMIVIMSWVSFWIKPEAAPARVTLGVTSLLTLSTQHAK 285
               |::.|  |::|:.::|..|..||...|..::.:.|:: |..:..:|:|.::.||:|:.....
  Fly   226 EPYLDITFNITMRRKTLFYTVNLIIPCMGISFLTILVFYL-PSDSGEKVSLSISILLSLTVFFLL 289

  Fly   286 SQSSLPPVS-----------YLKAVDAFMSVC-----------------------TVFV-----F 311
            ....:||.|           :...:|.| |:|                       |||:     |
  Fly   290 LAEIIPPTSLVVPLLGKFVLFTMILDTF-SICVTVLVLNIHFRSPQTHTMAPWVRTVFINQLPRF 353

  Fly   312 MALME--YCLINIVLSD-----------------TPIPKPMA-----YPPKPVA-GDGPKKE--- 348
            :.:..  |.:..::.|.                 .|:|.|:|     :.||..: ...|..:
  Fly   354 LVMRRPLYPISEMIKSSRRLMVRTCNGLELRDQIPPLPPPVALSRMHHSPKTTSRSTSPHLQHRV 418

  Fly   349 -------------GEGA-----------PPGGSNSTASKQQATMLPLAD 373
                         |.||           ||  :.|||::|.:|...|.|
  Fly   419 QTYNLMDECGMGMGGGASTITGHLSSLYPP--TMSTANQQTSTTSSLID 465

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ort	NP_524406.1	LIC	31..481	CDD:273305	94/476 (20%)
		Neur_chan_LBD	38..235	CDD:280998	46/235 (20%)
		Neur_chan_memb	243..>334	CDD:280999	26/148 (18%)
nAChRalpha3	NP_001285015.1	Neur_chan_LBD	26..241	CDD:280998	49/245 (20%)
		Neur_chan_memb	248..>359	CDD:280999	21/112 (19%)
		Neur_chan_memb	<683..760	CDD:280999

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR18945
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100