DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment ort and CG6927

DIOPT Version :9

Sequence 1:NP_524406.1 Gene:ort / 45910 FlyBaseID:FBgn0003011 Length:485 Species:Drosophila melanogaster
Sequence 2:NP_572194.1 Gene:CG6927 / 31419 FlyBaseID:FBgn0029733 Length:524 Species:Drosophila melanogaster


Alignment Length:516 Identity:118/516 - (22%)
Similarity:206/516 - (39%) Gaps:113/516 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly    39 RYDKMRPP---KKEGQ--PTIVYFHVTVMGLDSIDENSMTYVADVFFAQTWKDHRLRLPENMTQE 98
            |||::..|   .:.||  |..||....:..:.:::.:.:.:.........:.|.||.. .|::.:
  Fly    48 RYDRLERPITYSETGQRLPVDVYMRAYIYFMQNLEAHDLQFKIYALLQMRYLDPRLNF-RNVSPK 111

  Fly    99 YR--LLEVDWLKN-MWRPDSFFKNAKSVTFQTMTIPNHYMWLYKDKTILYMVKLTLKLSCIMNFA 160
            .|  :|..:.|:| :|.|..|..|.:..:...:|..:....:..|.|::...::...|.|.:|..
  Fly   112 RRQPILGEEHLRNSLWMPHIFLANERDSSILGLTEKDILTSISPDGTVIVSNRIKATLYCWLNLK 176

  Fly   161 IYPHDTQECKLQMESLSHTTDDLIFQWDPTTPLVVDENIELPQVALIR---NET---ADCTQVYS 219
            .:|.|.|.|...:||..:.|.:|:..|:...|:..|..:.|.:..|.|   |||   ||.:.:..
  Fly   177 KFPFDEQHCSTVLESWMYNTSELVLHWEQKRPITYDGALHLTEFVLQRSWSNETVINADLSDLRH 241

  Fly   220 ---TGNFTCLEVVFTLKRRLVYYVFNTYIPTCMIVIMSWVSFWIKPEAAPARVTLGVTSLLTLST 281
               .||::.|.....|.|.:.:|:.:.::|:.:||.:||||||::.:.||.|:|||.::|||..|
  Fly   242 GAFAGNYSSLSFTVHLTRVVGFYLMDYFLPSMLIVAISWVSFWLQADQAPPRITLGTSTLLTFIT 306

  Fly   282 QHAKSQSSLPPVSYLKAVDAFMSVCTVFVFMALMEYCLINIV-----------LSDTPIPKPMAY 335
            ..:....:||.|||:|..:.:...||:|:|.:::|:..:|.:           |:...|.|....
  Fly   307 LASAQGKTLPKVSYIKVSEVWFLGCTIFIFGSMVEFAFVNTIWRRKKSVPVKKLNSKHILKSTLS 371

  Fly   336 P----------PKPVAGDGPKKEGEGAPPGGSN-----------STASK-----QQATMLPLADE 374
            |          .:..:|....|..:....||:.           :|..:     ||.|...:...
  Fly   372 PNLLRRRSHARSRSFSGTALHKTADTGSLGGAGFNNYLTVNLPITTIKEGQVLDQQRTSRVVQKM 436

  Fly   375 KIEKIEKIFDEM------------------TKNRRIVTTTRRVVRPPLDADGPWIPRQESRIILT 421
            .:..:|..|..|                  |.|.|   |.....:..:|..| |           
  Fly   437 DVNFVESAFGSMGSAQSTGAISAASSSQTLTNNNR---TESAGHQEEIDLSG-W----------- 486

  Fly   422 PTIAPPPPPPQPAAPEPELPKPKLTPAQERLKRAIYIDRSSRVLFPALFASLNGIYWCVFY 482
                                 ..|||.:    .|::||..:|.:||..|...|..:|...|
  Fly   487 ---------------------TTLTPQE----IAMWIDSRARFVFPLSFLVFNLFFWTFVY 522

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ortNP_524406.1 LIC 31..481 CDD:273305 117/513 (23%)
Neur_chan_LBD 38..235 CDD:280998 50/212 (24%)
Neur_chan_memb 243..>334 CDD:280999 34/101 (34%)
CG6927NP_572194.1 LIC 3..520 CDD:273305 117/512 (23%)
Neur_chan_LBD 36..259 CDD:280998 50/211 (24%)
Neur_chan_memb 270..518 CDD:280999 64/287 (22%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3644
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 1 0.950 - 0 Normalized mean entropy S5256
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - P PTHR18945
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
43.860

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