Protein Alignment ort and GABRD

DIOPT Version :9

• Sequence 1: NP_524406.1
• Gene: ort / 45910
• FlyBaseID: FBgn0003011
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: XP_016856425.1
• Gene: GABRD / 2563
• HGNCID: 4084
• Length: 687
• Species: Homo sapiens
• Alignment Length: 460
• Identity: 134/460 - (29%)
• Similarity: 210/460 - (45%)
• Gaps: 72/460 - (15%)

  Fly    37 IKRYDKMRPPKKEGQPTIVYFHVTVMGLDSIDENSMTYVADVFFAQTWKDHRLRLPENMTQEYRL 101
            |..|.:...|...|.|..|...:.|..:|.|.|.:|.|...||..|:|:|.||..  |.|.|...
Human   283 IAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSY--NHTNETLG 345

  Fly   102 LEVDWLKNMWRPDSFFKNAKSVTFQTMTIPNHYMWLYKDKTILYMVKLTLKLSCIMNFAIYPHDT 166
            |:..::..:|.||:|..||||..|..:|:.|..:.|..|..|||.:::|..::|.|:.|.||.|.
Human   346 LDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVACDMDLAKYPMDE 410

  Fly   167 QECKLQMESLSHTTDDLIFQWDPTTPLVVD-ENIELPQVALIRNE-TADCTQVYSTGNFTCLEVV 229
            |||.|.:||..::::|:::.|..:...:.. :.::|.|..:.... |.:.....|.|.|..|.:.
Human   411 QECMLDLESYGYSSEDIVYYWSESQEHIHGLDKLQLAQFTITSYRFTTELMNFKSAGQFPRLSLH 475

  Fly   230 FTLKRRLVYYVFNTYIPTCMIVIMSWVSFWIKPEAAPARVTLGVTSLLTLSTQHAKSQSSLPPVS 294
            |.|:|....|:..:|:|:.::|.||||||||...|.||||:||:|::||::|....::||||..|
Human   476 FHLRRNRGVYIIQSYMPSVLLVAMSWVSFWISQAAVPARVSLGITTVLTMTTLMVSARSSLPRAS 540

  Fly   295 YLKAVDAFMSVCTVFVFMALMEYCLINIVLSDTPIPKPMAYPPKPVAGDGPKKEGEGAPPGGSNS 359
            .:||:|.:..:|.||||.||:||...:.                                   |:
Human   541 AIKALDVYFWICYVFVFAALVEYAFAHF-----------------------------------NA 570

  Fly   360 TASKQQATMLPLADEKIEKIEKIFDEMTKNRRIV-------------TTTRRVVRPPLDADGPWI 411
            ...|:|...:        |:.:...||.....||             ..:||..|.|.:..|.:
Human   571 DYRKKQKAKV--------KVSRPRAEMDVRNAIVLFSLSAAGVTQELAISRRQRRVPGNLMGSY- 626

  Fly   412 PRQESRIILTPTIAPPPPPPQPAAPEPELPKPKLTPAQERLKRAIYIDRSSRVLFPALFASLNGI 476
                 |.:...|..........:..:..: :.:|.|..     |..||..:|.:|||.||::|.|
Human   627 -----RSVGVETGETKKEGAARSGGQGGI-RARLRPID-----ADTIDIYARAVFPAAFAAVNVI 680

  Fly   477 YWCVF 481
            ||..:
Human   681 YWAAY 685

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ort	NP_524406.1	LIC	31..481	CDD:273305	134/458 (29%)
		Neur_chan_LBD	38..235	CDD:280998	62/198 (31%)
		Neur_chan_memb	243..>334	CDD:280999	39/90 (43%)
GABRD	XP_016856425.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810