Protein Alignment ort and Gabrb1

DIOPT Version :10

• Sequence 1: NP_524406.1
• Gene: ort / 45910
• FlyBaseID: FBgn0003011
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: NP_037088.1
• Gene: Gabrb1 / 25450
• RGDID: 2649
• Length: 474
• Species: Rattus norvegicus
• Alignment Length: 512
• Identity: 146/512 - (28%)
• Similarity: 245/512 - (47%)
• Gaps: 87/512 - (16%)

  Fly     3 FQIIILVICTICMKHYAKGEFQQSLAITDILPEDIKRYDKMRPPKKEGQPTIVYFHVTVMGLDSI 67
            |.:::.::|  |.  ::..|......:.:.:...:|.||....|...|.|..|...:.|..:|.:
  Rat    15 FPVMVAMVC--CA--HSSNEPSNMSYVKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVASIDMV 75

  Fly    68 DENSMTYVADVFFAQTWKDHRLR---LPENMTQEYRLLEVDWLKNMWRPDSFFKNAKSVTFQTMT 129
            .|.:|.|...::|.|:|||.||.   :|.|:|.:.|:.:     .:|.||::|.|.|......:|
  Rat    76 SEVNMDYTLTMYFQQSWKDKRLSYSGIPLNLTLDNRVAD-----QLWVPDTYFLNDKKSFVHGVT 135

  Fly   130 IPNHYMWLYKDKTILYMVKLTLKLSCIMNFAIYPHDTQECKLQMESLSHTTDDLIFQWDPTTPLV 194
            :.|..:.|:.|.|:||.:::|...:|:|:...||.|.|.|.|::||..:||||:.|.|:.....|
  Rat   136 VKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWNGGEGAV 200

  Fly   195 VDEN-IELPQVALIRNETADCTQVYSTGNFTCLEVVFTLKRRLVYYVFNTYIPTCMIVIMSWVSF 258
            ...| |||||.:::..:.......::||.:..|.:.|.|||.:.|::..||:|:.:|.|:|||||
  Rat   201 TGVNKIELPQFSIVDYKMVSKKVEFTTGAYPRLSLSFRLKRNIGYFILQTYMPSTLITILSWVSF 265

  Fly   259 WIKPEAAPARVTLGVTSLLTLSTQHAKSQSSLPPVSYLKAVDAFMSVCTVFVFMALMEYCLINIV 323
            ||..:|:.|||.||:|::||::|.....:.:||.:.|:||:|.::..|.||||:||:||..:|.:
  Rat   266 WINYDASAARVALGITTVLTMTTISTHLRETLPKIPYVKAIDIYLMGCFVFVFLALLEYAFVNYI 330

  Fly   324 LSDTPIPKPMAYPPKPVAGDGPKKEGEGAPPGGSNSTASKQQATMLPLADEKIEKIEKIFDEMTK 388
            .                .|.||:|:|           ||||..:    |:|| .|:|....::..
  Rat   331 F----------------FGKGPQKKG-----------ASKQDQS----ANEK-NKLEMNKVQVDA 363

  Fly   389 NRRIVTTTRRVVRPPLDADGPWIPRQES--RIILTPTIAPPPPPPQPAAPEPELPKPKLT----- 446
            :..|:.:|..:             |.|:  ..:||....|........:...:..||..:
  Rat   364 HGNILLSTLEI-------------RNETSGSEVLTGVSDPKATMYSYDSASIQYRKPLSSREGFG 415

  Fly   447 --------PAQERLKRAI--------------YIDRSSRVLFPALFASLNGIYWCVF 481
                    |.:.|::|..              .||:.||:.||..|:..|.:||..:
  Rat   416 RGLDRHGVPGKGRIRRRASQLKVKIPDLTDVNSIDKWSRMFFPITFSLFNVVYWLYY 472

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ort	NP_524406.1	LIC	31..481	CDD:455710	142/482 (29%)
		LGIC_ECD_HisCl	51..235	CDD:349793	61/187 (33%)
		Cys-loop	155..169	CDD:349793	6/13 (46%)
Gabrb1	NP_037088.1	LIC	9..472	CDD:273305	146/510 (29%)