DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment ort and Gabrp

DIOPT Version :9

Sequence 1:NP_524406.1 Gene:ort / 45910 FlyBaseID:FBgn0003011 Length:485 Species:Drosophila melanogaster
Sequence 2:NP_666129.1 Gene:Gabrp / 216643 MGIID:2387597 Length:440 Species:Mus musculus


Alignment Length:469 Identity:129/469 - (27%)
Similarity:212/469 - (45%) Gaps:101/469 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly    40 YDKMRPPKKEGQPTIVYFHVTVMGLDSIDENSMTYVADVFFAQTWKDHRLRLPEN--MTQEYRLL 102
            |:|...|...|.|..:...:.:..:.||.|::|.|.|.::..|.|.|.||....|  .|.:.||:
Mouse    48 YNKFLRPNFGGDPVRIALTLDIASISSISESNMDYTATIYLRQRWTDPRLVFEGNKSFTLDARLV 112

  Fly   103 EVDWLKNMWRPDSFFKNAKSVTFQTMTIPNHYMWLYKDKTILYMVKLTLKLSCIMNFAIYPHDTQ 167
            |.     :|.||::...:|......:|:.|..:.|:.:.|:||.:::|..::|.|:.:.||.|||
Mouse   113 EF-----LWVPDTYIVESKKSFLHEVTVGNRLIRLFSNGTVLYALRITTTVTCNMDLSKYPMDTQ 172

  Fly   168 ECKLQMESLSHTTDDLIFQW----DPTTPLVVDENIELPQVALIRNETADCTQVYSTGNFTCLEV 228
            .||||:||..:..:|:.|.|    |....|   ||:.|.|..:.:..|........|||:|.|.:
Mouse   173 TCKLQLESWGYDGNDVEFSWLRGNDSVRGL---ENLRLAQYTIQQYFTLVTVSQQETGNYTRLVL 234

  Fly   229 VFTLKRRLVYYVFNTYIPTCMIVIMSWVSFWIKPEAAPARVTLGVTSLLTLSTQHAKSQSSLPPV 293
            .|.|:|.::|::..||:|:..:|::|||||||..::.|||..:|||::|:::|....|::|||..
Mouse   235 QFELRRNVLYFILETYVPSTFLVVLSWVSFWISLDSVPARTCIGVTTVLSMTTLMIGSRTSLPNT 299

  Fly   294 S-YLKAVDAFMSVCTVFVFMALMEYCLINIVLSDTPIPKPMAYPPKPVAGDGPKKEGEGAPPGGS 357
            : ::||:|.::.:|..|||.||:||.:.:.          .:.....|...||.|:.|..     
Mouse   300 NCFIKAIDVYLGICFSFVFGALLEYAVAHY----------SSLQQMAVKDRGPAKDSEEV----- 349

  Fly   358 NSTASKQQATMLPLADEKIEKIEKIFDEMTKNRRIVTTTRRVVRPPLDADG-------------- 408
                                .|..|.     |..|.:..|::....::..|              
Mouse   350 --------------------NITNII-----NSSISSFKRKISFASIEISGDNVNYSDLTMKASD 389

  Fly   409 --PWIPRQE-SRIILTPTIAPPPPPPQPAAPEPELPKPKLTPAQERLKRAIYIDRSSRVLFPALF 470
              .::.|:: ||||...||..|.                            .:||.|::|||.:|
Mouse   390 KFKFVFREKISRIIDYFTIQNPS----------------------------NVDRYSKLLFPLIF 426

  Fly   471 ASLNGIYWCVFYEY 484
            ...|..|| .:|.|
Mouse   427 MLANVFYW-AYYMY 439

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ortNP_524406.1 LIC 31..481 CDD:273305 127/464 (27%)
Neur_chan_LBD 38..235 CDD:280998 62/200 (31%)
Neur_chan_memb 243..>334 CDD:280999 34/91 (37%)
GabrpNP_666129.1 Neur_chan_LBD 41..242 CDD:280998 63/201 (31%)
LIC 43..437 CDD:273305 127/465 (27%)
Neur_chan_memb 249..434 CDD:280999 61/252 (24%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3644
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
32.810

Return to query results.
Submit another query.