Protein Alignment ort and Gabrr3

DIOPT Version :10

• Sequence 1: NP_524406.1
• Gene: ort / 45910
• FlyBaseID: FBgn0003011
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: NP_620252.1
• Gene: Gabrr3 / 192258
• RGDID: 621564
• Length: 464
• Species: Rattus norvegicus
• Alignment Length: 473
• Identity: 130/473 - (27%)
• Similarity: 212/473 - (44%)
• Gaps: 101/473 - (21%)

  Fly    37 IKRYDKMRPPKKEGQPTIVYFHVTVMGLDSIDENSMTYVADVFFAQTWKDHRLRLP----ENMTQ 97
            |:.:|....|...|.|..|...|.|..:|||.|.:|.:....:....|||.||..|    ::||.
  Rat    64 IEDHDFSTRPGFGGSPVPVGIDVQVESIDSISEVNMDFTMTFYLRHYWKDERLSFPSTTNKSMTF 128

  Fly    98 EYRLLEVDWLKNMWRPDSFFKNAKSVTFQTMTIPNHYMWLYKDKTILYMVKLTLKLSCIMNFAIY 162
            :.||::     .:|.||.||.::|.......|:.|..:.::.|..:|:.:::|:...|.|:|:.:
  Rat   129 DRRLIQ-----KIWVPDIFFVHSKRSFIHDTTVENIMLRVHPDGNVLFSLRITVSAMCFMDFSRF 188

  Fly   163 PHDTQECKLQMESLSHTTDDLIFQW-DPTTPLVVDENIELPQVALIRNETADCTQVY-STGNFTC 225
            |.|||.|.|::||.::..:||:..| .....|..:|:|.|.|..:.....:.....| |||.:..
  Rat   189 PLDTQNCSLELESYAYNEEDLMLYWKHGNKSLNTEEHISLSQFFIEEFSASSGLAFYSSTGWYYR 253

  Fly   226 LEVVFTLKRRLVYYVFNTYIPTCMIVIMSWVSFWIKPEAAPARVTLGVTSLLTLSTQHAKSQSSL 290
            |.:.|.|:|.:.::|..||.|..::|::|||||||...|.||||:||:|::||:||......:|:
  Rat   254 LFINFVLRRHIFFFVLQTYFPAMLMVMLSWVSFWIDRRAVPARVSLGITTVLTMSTIVTGVSASM 318

  Fly   291 PPVSYLKAVDAFMSVCTVFVFMALMEYCLINIV-----------------LSDTPIPKPMAYPPK 338
            |.|||:||||.:|.|.::|||::::||..:|.:                 :.:....:.||:
  Rat   319 PQVSYVKAVDVYMWVSSLFVFLSVIEYAAVNYLTTVEEWKQLNRRGKISGMYNIDAVQAMAF--- 380

  Fly   339 PVAGDGPKKEGEGAPPGGSNSTASKQQATMLPLADEKIEKIEKIFDEMTKNRRIVTTTRRVVRPP 403
                ||...:||         |...|.:..|...::.:.                  |:....|
  Rat   381 ----DGCYHDGE---------TDVDQTSFFLHSEEDSMR------------------TKFTGSP- 413

  Fly   404 LDADGPWIPRQE-----SRIILTPTIAPPPPPPQPAAPEPELPKPKLTPAQERLKRAIYIDRSSR 463
             .||...|.|:.     .|||                                |:....||..||
  Rat   414 -CADSSQIKRKSLGGNVGRII--------------------------------LENNHVIDTYSR 445

  Fly   464 VLFPALFASLNGIYWCVF 481
            ::||.::...|..||.::
  Rat   446 IVFPVVYIIFNLFYWGIY 463

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ort	NP_524406.1	LIC	31..481	CDD:455710	130/471 (28%)
		LGIC_ECD_HisCl	51..235	CDD:349793	56/189 (30%)
		Cys-loop	155..169	CDD:349793	7/13 (54%)
Gabrr3	NP_620252.1	LIC	58..463	CDD:455710	130/471 (28%)
		LGIC_ECD	79..264	CDD:475126	57/189 (30%)
		Interaction with SQSTM1. /evidence=ECO:0000269|PubMed:12431995	344..445		24/168 (14%)