Protein Alignment ort and lgc-56

DIOPT Version :10

• Sequence 1: NP_524406.1
• Gene: ort / 45910
• FlyBaseID: FBgn0003011
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: NP_494951.3
• Gene: lgc-56 / 191638
• WormBaseID: WBGene00001588
• Length: 445
• Species: Caenorhabditis elegans
• Alignment Length: 510
• Identity: 128/510 - (25%)
• Similarity: 198/510 - (38%)
• Gaps: 115/510 - (22%)

  Fly     5 IIILVICTICMK----------HYAKGEFQQSLAITDILPEDIKRYDKMRPPKKEGQPTIVYFHV 59
            |.:|:|.|:..:          |.......:...:||:|.:    |||...|........|  .:
 Worm     6 IYMLLISTVAKEVKTESLVDPAHCEYNSNHRKSILTDLLQD----YDKTMVPSNNSVQVSV--EL 64

  Fly    60 TVMGLDSIDENSMTYVADVFFAQTWKDHRLRLPENMTQEYR------LLEVDWL--KNMWRPDSF 116
            ||..:.||.|.|.:::|||:|:|.|.|.||        |||      .|.:|..  :.:|.|:..
 Worm    65 TVQDISSISEISSSFIADVWFSQVWYDPRL--------EYRNISCKTNLSLDSYVSERLWTPNVC 121

  Fly   117 FKNAKSVTFQTMTIPNHYMWLYKDKTILYMVKLTLKLSCIMNFAIYPHDTQECKLQMESLSHTTD 181
            |.|:||.........|..:.:|.:.|:....::.:...|....:.:|.|.|||.|..||.|:...
 Worm   122 FVNSKSTQVHKSPASNILLIIYPNGTVWLNYRVQVSAPCSFELSRFPIDAQECHLVFESYSYNIA 186

  Fly   182 DLIFQWDPTTPLVV--DENIELPQVALIRNETADCTQVYSTGNFTCLEVVFTLKRRLVYYVFNTY 244
            ::...|....|:.:  .|:..||............:..|:.|.:..|:|.|..||...|||...|
 Worm   187 EVRLNWQQWAPVTMPPPEDFRLPDFQFYNVTWGKTSNEYTAGMWDQLKVTFRFKRLYGYYVLQMY 251

  Fly   245 IPTCMIVIMSWVSFWIKPEAAPARVTLGVTSLLTLSTQHAKSQSSLPPVSYLKAVDAFMSVCTVF 309
            :||.:.|.:||::|||...|.|||:||||:||:.|:.|......:||.||::||:|.:..||..|
 Worm   252 LPTYLSVFISWIAFWIDTRALPARITLGVSSLMALTFQFGNIVKNLPRVSFVKAIDLWFFVCVAF 316

  Fly   310 VFMALMEYCLINIVLSDTPIPK-------PMAYPPKPVAGDGP---KKEGEGAPPGGSNSTASKQ 364
            :|.:|:|..::..|...|.|.:       ..|.....:..|.|   :|          .|..||.
 Worm   317 IFFSLVELAVVGFVDKITEIKRRSRRIKFQRAIAGGTIKNDRPVSFRK----------YSCTSKC 371

  Fly   365 QATMLPLADEKIEKIEKIFDEMTKNRRIVTTTRRVVRPPLDADGPWIPRQESRIILTPTIAPPPP 429
            .:....:.:...|::..|..|...|                 ...|
 Worm   372 NSVRYNINNNDDEELYNISGETNGN-----------------GVSW------------------- 400

  Fly   430 PPQPAAPEPELPKPKLTPAQERLKRAIYIDRSSRV------LFPALFASLNGIYW 478
                               :....|....|..:||      .|||:||:.|..||
 Worm   401 -------------------KNNSSREASADMGARVDSFAAKAFPAMFAAFNVFYW 436

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ort	NP_524406.1	LIC	31..481	CDD:455710	122/474 (26%)
		LGIC_ECD_HisCl	51..235	CDD:349793	51/193 (26%)
		Cys-loop	155..169	CDD:349793	4/13 (31%)
lgc-56	NP_494951.3	LIC	39..439	CDD:455710	123/477 (26%)
		LGIC_ECD_GABAAR	58..241	CDD:349791	50/192 (26%)
		Cys-loop	160..174	CDD:349791	4/13 (31%)