Protein Alignment ort and lgc-45

DIOPT Version :9

• Sequence 1: NP_524406.1
• Gene: ort / 45910
• FlyBaseID: FBgn0003011
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: NP_001335538.1
• Gene: lgc-45 / 189345
• WormBaseID: WBGene00021146
• Length: 1046
• Species: Caenorhabditis elegans
• Alignment Length: 457
• Identity: 119/457 - (26%)
• Similarity: 195/457 - (42%)
• Gaps: 103/457 - (22%)

  Fly    32 ILPE-DIKRYDKMRPP-KKEGQPTIVYFHVTVMGLDSIDENSMTYVADVFFAQTWKDHRLRLPEN 94
            |||. :..:||....| ..:|...:|.|.:.:..:.:...::|.|..|::...:|:|.||..|.:
 Worm   678 ILPVLNKNQYDPFSAPIVFQGSAVVVRFGIYIESMSNFQTSTMDYDMDIYLMMSWRDARLVNPYD 742

  Fly    95 MTQEYRLLEVDWLKNMWRPDSFFKNAKSVTFQTMTIPNHYMWLYKDKTILYMVKLTLKLSCIMNF 159
              :...:.|.|.|:.:||||.||.|||...|..:|..|..|.::.|..:||..::.:|.||.:..
 Worm   743 --KPILVKEEDILEKIWRPDPFFANAKEAEFHEVTFLNFLMRIFPDGLVLYETRVKIKPSCNLIL 805

  Fly   160 AIYPHDTQECKLQMESLSHTTDDLIFQWDPTTPLVVDEN--IELPQVALIRNETADCTQVYSTGN 222
            ..||||.|.|.|.::|.::..:.:.|:|.......:|:|  ::||::.:.|.||..|.....:|.
 Worm   806 CKYPHDKQTCDLLIKSFAYPVETVRFEWFTRRKDAIDKNPDVKLPELYIDRYETTTCPNERKSGA 870

  Fly   223 FTCLEVVFTLKRRLVYYVFNTYIPTCMIVIMSWVSFWIKPEAAPARVTLGVTSLLTLSTQHAKSQ 287
            |:||..||.|||.:.:::..|||||.:.::.|||..|:..|....|:.:.:|.||||||:.|.::
 Worm   871 FSCLRAVFRLKRDVGFHIAQTYIPTSLALMFSWVGVWLPEEFMEGRIGVAITVLLTLSTESAGAR 935

  Fly   288 SSLPPVSYLKAVDAFMSVCTVFVFMALMEYCLINIVLSDTPIPKPMAYPPKPVAGDGPKKEGEGA 352
            ..||.||||||:|.:....|.|||..|::
 Worm   936 EHLPSVSYLKAIDLWFGFITGFVFFTLLQ------------------------------------ 964

  Fly   353 PPGGSNSTASKQQATMLPLA-DEKIEKIEKIFDEMTKNRRIVTTTRRVVRPPLDADGPWIPRQES 416
                          |:..:. |::..:::|                            |..|:.:
 Worm   965 --------------TLFVIGFDKRANQLKK----------------------------WAGRKTA 987

  Fly   417 RIILTPTIAPPPPPPQPAAPEPELPKPKLTPAQERLKRAIYIDRSSRVLFPALFASLNGIYWCVF 481
            .|                  ..|:.:..|..|....|...|:|...||.:|..|.....:|:.||
 Worm   988 DI------------------TEEIREALLQKATRYHKTGRYLDNFCRVFYPLSFILFLLMYYFVF 1034

  Fly   482 YE 483
            .|
 Worm  1035 TE 1036

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ort	NP_524406.1	LIC	31..481	CDD:273305	116/453 (26%)
		Neur_chan_LBD	38..235	CDD:280998	62/199 (31%)
		Neur_chan_memb	243..>334	CDD:280999	33/90 (37%)
lgc-45	NP_001335538.1	Neur_chan_LBD	687..>969	CDD:332142	97/333 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18945
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	5	4.870