Protein Alignment ort and glc-4

DIOPT Version :10

• Sequence 1: NP_524406.1
• Gene: ort / 45910
• FlyBaseID: FBgn0003011
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: NP_495489.2
• Gene: glc-4 / 182971
• WormBaseID: WBGene00001594
• Length: 500
• Species: Caenorhabditis elegans
• Alignment Length: 527
• Identity: 132/527 - (25%)
• Similarity: 225/527 - (42%)
• Gaps: 141/527 - (26%)

  Fly    23 FQQSLAITDILPEDIKRYD-KMRP----PKKEGQPTI-VYFHVTVMGLDSIDENSMTYVADVFFA 81
            :::.:.:.|:|.:    || .:||    |..:.:..: |...:.:..:.::.|.:|.:||...|.
 Worm    42 WREQMTVCDLLQD----YDAAVRPSGRTPYNDTRGAVMVTTSLNIRSISAVSEKNMEFVAQFRFR 102

  Fly    82 QTWKDHRLRLPEN---MTQEYR---LLEVDWLKNMWRPDSFFKNAKSVTFQTMTIPNHYMWLYKD 140
            |.|.|.|||..|:   ::.:||   .:.|...:::|.||:||:|.|:..:..:...|.::.:..|
 Worm   103 QEWYDDRLRFIEHQGLLSSDYRNFEFIHVARDQSLWIPDTFFQNEKNGWYHMLNQENRFLKIRSD 167

  Fly   141 KTILYMVKLTLKLSCIMNFAIYPHDTQECKLQMESLSHTTDDLIFQWD-PTTPLVVDENIELPQV 204
            ..::|..:|||.|:|.|:.:.||.|.|.|::...|.::||.|:.:.|| |...:....|..||..
 Worm   168 GKLIYDRRLTLHLACSMHLSRYPMDHQNCEIAFASYAYTTADIEYIWDVPAIQIHEGANGALPNF 232

  Fly   205 ALIRNETADCTQVYSTGNFTCLEVVFTLKRRLVYYVFNTYIPTCMIVIMSWVSFWIKPEAAPARV 269
            .:...:.|.||...:||.::||:|...|.|...:::...|||:.|:|.::|||:||..::..|||
 Worm   233 EIASFKNASCTSKTNTGTYSCLKVEIRLNRVFSFFLLQLYIPSSMLVGVAWVSYWIDWKSTAARV 297

  Fly   270 TLGVTSLLTLSTQHAKSQSSLPPVSYLKAVDAFMSVCTVFVFMALMEYCLINIV----------- 323
            .|.:.:|||:.|......|:||||||.|::|.::..|.||:|.:|:||.::|.|
 Worm   298 PLAIVTLLTMITTSHAINSNLPPVSYAKSIDIWVGACVVFIFFSLIEYAVVNYVGILDEHRQMKK 362

  Fly   324 -----------------------LSDTPIPKPMAYPPKPVAGDGPKKEGEGAPPGGSNSTASKQQ 365
                                   |:.:|..|      |.:....|||..|            .|:
 Worm   363 AACNRSRLSNVIENDNFGESLQSLTFSPQEK------KRLIRRRPKKNME------------MQE 409

  Fly   366 ATMLPLADEKIEKIEK-------------IFDEMT------KNRRIVTTTRRVVRPPLDADGPWI 411
            ...     |.||.:::             .|.:.|      :.:|:     .:||        |.
 Worm   410 GDF-----EAIEMVDRGPPRSAGLMEEGWTFHDTTDLVYIGQRKRV-----ELVR--------WC 456

  Fly   412 PRQESRIILTPTIAPPPPPPQPAAPEPELPKPKLTPAQERLKRAIYIDRSSRVLFPALFASLNGI 476
            ....||                                   .||..||..:|::||..|...|..
 Worm   457 SVLSSR-----------------------------------GRAERIDIIARIIFPLAFILFNFA 486

  Fly   477 YWCVFYE 483
            ||.::.|
 Worm   487 YWSIYLE 493

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ort	NP_524406.1	LIC	31..481	CDD:455710	131/515 (25%)
		LGIC_ECD_HisCl	51..235	CDD:349793	56/191 (29%)
		Cys-loop	155..169	CDD:349793	6/13 (46%)
glc-4	NP_495489.2	LIC	26..491	CDD:455710	131/523 (25%)