Protein Alignment ort and gab-1

DIOPT Version :9

• Sequence 1: NP_524406.1
• Gene: ort / 45910
• FlyBaseID: FBgn0003011
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: NP_499661.2
• Gene: gab-1 / 176691
• WormBaseID: WBGene00001512
• Length: 550
• Species: Caenorhabditis elegans
• Alignment Length: 518
• Identity: 145/518 - (27%)
• Similarity: 235/518 - (45%)
• Gaps: 89/518 - (17%)

  Fly    26 SLAITDILPEDIKRYDKMRPPKKEGQPTIVYFHVTVMGLDSIDENSMTYVADVFFAQTWKDHRLR 90
            |..::|:|.:    ||....|...|...::...:.:...|||.|..|.|...::..|.|.|.|||
 Worm    55 SSLLSDLLLD----YDIRLRPGFGGDALLLTMDIIIASFDSISEVDMDYTLTMYLHQYWTDERLR 115

  Fly    91 LPENMTQEYRLLEVDWLKNMWRPDSFFKNAKSVTFQTMTIPNHYMWLYKDKTILYMVKLTLKLSC 155
            ....:..:...|..::.:|:|.||:|..|.|......:|..|..:.:..|..:.|.::||..|||
 Worm   116 WSNEIPIDEMTLSGEFSQNIWVPDTFLANDKHSYLHEVTERNKMLRINVDGKVAYGMRLTSTLSC 180

  Fly   156 IMNFAIYPHDTQECKLQMESLSHTTDDLIFQWDPTTPLVVD--ENIELPQVALIRNETADCTQVY 218
            .||...:|.|:|.|.:::||..:||.:::.:|:  .||.|.  |..::||..:....|.|.....
 Worm   181 SMNLRNFPLDSQNCTVEIESYGYTTSEVLMKWN--YPLAVHGVEQADVPQFTITGFHTEDSIVST 243

  Fly   219 STGNFTCLEVVFTLKRRLVYYVFNTYIPTCMIVIMSWVSFWIKPEAAPARVTLGVTSLLTLSTQH 283
            :||::..|.:||.|:|.:.|::|.||:|..:||::|||||||..||..|||.||:|::||::|..
 Worm   244 ATGSYQRLSLVFQLRRSVGYFIFQTYLPCVLIVMLSWVSFWINHEATSARVALGITTVLTMTTIS 308

  Fly   284 AKSQSSLPPVSYLKAVDAFMSVCTVFVFMALMEYCLINIVLSDTPIPKPMAYPPKPVAGDGPKKE 348
            ...:.|||.:||:|::|.::.:|.||||.||:||..:|.........|.......||.| ..|::
 Worm   309 TGVRQSLPRISYVKSIDIYLVMCFVFVFAALLEYAAVNYSYWGRERGKGGGGNEWPVNG-ANKED 372

  Fly   349 GEGA-------PPGGSNSTASKQQATMLPLADEKIEKIEKIF---DEMTKNRRIVTTTRRVVR-- 401
            .|.|       |.|..:.....|        |.::|.:|:..   :...:|....:|::...|
 Worm   373 RESAVNVQKWVPSGLMDGVPQPQ--------DRRVEALEEAMSTSNTAAQNNNFESTSKPKKRSS 429

  Fly   402 ---PPL---------DADGPWIPRQESRIILTPTIAPPPPPPQPAAPEPEL-------------- 440
               |||         :::.|..||..:..:            :.|.|...|
 Worm   430 SPIPPLCRAGNTISEESESPDYPRYSTTSL------------KGARPHASLNHKTHHLKGRSSAR 482

  Fly   441 PKPKLTPAQ-------------ERLKRAI---------YIDRSSRVLFPALFASLNGIYWCVF 481
            .|.::|.|:             .|.::.|         .||:.|||:||..|...|..||..:
 Worm   483 AKRRMTLARMNVSMKQSISGIGRRARKVIPTIRVRDVNLIDKYSRVVFPVCFIVFNLFYWSYY 545

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ort	NP_524406.1	LIC	31..481	CDD:273305	144/511 (28%)
		Neur_chan_LBD	38..235	CDD:280998	58/198 (29%)
		Neur_chan_memb	243..>334	CDD:280999	41/90 (46%)
gab-1	NP_499661.2	LIC	67..545	CDD:273305	140/500 (28%)
		Neur_chan_LBD	68..259	CDD:280998	56/192 (29%)
		Neur_chan_memb	268..542	CDD:280999	79/294 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810