Protein Alignment ort and lgc-34

DIOPT Version :10

• Sequence 1: NP_524406.1
• Gene: ort / 45910
• FlyBaseID: FBgn0003011
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: NP_493752.1
• Gene: lgc-34 / 173443
• WormBaseID: WBGene00020836
• Length: 390
• Species: Caenorhabditis elegans
• Alignment Length: 338
• Identity: 67/338 - (19%)
• Similarity: 147/338 - (43%)
• Gaps: 40/338 - (11%)

  Fly     2 VFQIIILVICTICMKHYAKGEFQQSLAITD--ILPEDIKRYD-KMRPPKKEGQPTIVYFHVTVMG 63
            :|..::|:...:|.   |:..|......|:  |:...:..|| ..|||.::.........:|.:.
 Worm     4 IFLFLVLLSIGVCS---AQKAFHSRRLGTEGQIVGRILSEYDSSSRPPVRDHADNSAILVITNIF 65

  Fly    64 LDSIDENSMTYVADVFFAQTWKDHRLRLPENMTQEYRLLEVDWLKNMWRPDSFF----------K 118
            ::.:..::.....|::..|.|:|.||:...:..:....:.:...:.:|.||::|          |
 Worm    66 INRLIWHNNYAEVDLYLRQQWQDSRLKYDVDTREGIDEIRLPGNRKIWEPDTYFTSGKELSRNEK 130

  Fly   119 NAKSVTFQTMTIPNHYMWLYKDKTILYMVKLTLKLSCIMNFAIYPHDTQECKLQMESLSHTTDDL 183
            |:|.:..:    |:.|  :...:.:|  ::|......:..|.    ::::..:::.|.::..||:
 Worm   131 NSKHIVVE----PSGY--IRSSERVL--LELPYAYGTMFPFT----NSRQFTIKLGSYNYDIDDI 183

  Fly   184 IFQWDPTTPLVVDENIELPQVALIRNET------ADCTQVYSTGNFTCLEVVFTLKRRLVYYVFN 242
            ::.|..:.|||  ..||:.|..|..:.|      .||...|:.|.::|::.........:..:.:
 Worm   184 VYLWANSPPLV--NPIEVSQDLLKGDLTFEEASAGDCVGNYTVGVYSCIDAHVYFSASTISGLMS 246

  Fly   243 TYIPTCMIVIMSWVSFWIKPEAAPARVTLGVTSLLTLSTQHAKSQSSLPPVSYLKAVDAFMSVCT 307
            .::|:..::|.||:.|||....:..|..........|:..:...:..    ||.:|..|:::.|.
 Worm   247 WFLPSLFLLIGSWLHFWIHGSWSVPRTISAAVPFFILAAYYIFMRED----SYTQAQGAWLAFCL 307

  Fly   308 VFVFMALMEYCLI 320
            |..|.:.:||.|:
 Worm   308 VLTFFSFVEYFLV 320

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ort	NP_524406.1	LIC	31..481	CDD:455710	61/309 (20%)
		LGIC_ECD_HisCl	51..235	CDD:349793	36/199 (18%)
		Cys-loop	155..169	CDD:349793	1/13 (8%)
lgc-34	NP_493752.1	LIC	1..388	CDD:455710	67/338 (20%)
		LGIC_ECD_anion	58..237	CDD:349788	36/192 (19%)
		Cys-loop	155..169	CDD:349788	1/17 (6%)