Protein Alignment ort and Gabrr2

DIOPT Version :10

• Sequence 1: NP_524406.1
• Gene: ort / 45910
• FlyBaseID: FBgn0003011
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: NP_001407795.1
• Gene: Gabrr2 / 14409
• MGIID: 95626
• Length: 499
• Species: Mus musculus
• Alignment Length: 501
• Identity: 141/501 - (28%)
• Similarity: 230/501 - (45%)
• Gaps: 110/501 - (21%)

  Fly    23 FQQSLAITDILPEDIKRYDKMRPPKKE----------------GQPTI-VYFHVTVMGLDSIDEN 70
            ::::|.:|           ||||.|..                |.|.| |...|.|..||||.|.
Mouse    66 YKKNLDVT-----------KMRPGKPRPLLRVEDHDFTMRPAFGGPAIPVGVDVQVESLDSISEV 119

  Fly    71 SMTYVADVFFAQTWKDHRLRLP----ENMTQEYRLLEVDWLKNMWRPDSFFKNAKSVTFQTMTIP 131
            .|.:...::....|:|.||..|    ::||.:.||     :|.:|.||.||.::|.......|..
Mouse   120 DMDFTMTLYLRHYWRDERLAFPSSSNKSMTFDGRL-----VKKIWVPDVFFVHSKRSFIHDTTTD 179

  Fly   132 NHYMWLYKDKTILYMVKLTLKLSCIMNFAIYPHDTQECKLQMESLSHTTDDLIFQW-DPTTPLVV 195
            |..:.::.|..:||.:::|:...|.|:|:.:|.|:|.|.|::||.::|.:||:..| :....|..
Mouse   180 NIMLRVFPDGHVLYSMRITVTAMCNMDFSHFPLDSQTCSLELESYAYTDEDLMLYWKNGDESLKT 244

  Fly   196 DENIELPQVALIRNETADCTQVY-STGNFTCLEVVFTLKRRLVYYVFNTYIPTCMIVIMSWVSFW 259
            ||.|.|.|..:.:..|......| |||.:..|.:.|||:|.:.:::..||.|..::|::||||||
Mouse   245 DEKISLSQFLIQKFHTTSRLAFYSSTGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSFW 309

  Fly   260 IKPEAAPARVTLGVTSLLTLSTQHAKSQSSLPPVSYLKAVDAFMSVCTVFVFMALMEYCLINIVL 324
            |...|.||||:||:.::||:||......:|:|.|||::|||.::.|..||||::::||..:|.:.
Mouse   310 IDHRAVPARVSLGIMTVLTMSTIITGVNASMPRVSYIRAVDIYLWVSFVFVFLSVLEYAAVNYLT 374

  Fly   325 S---------DTPIPKPMAYPPKP-VAG---------DGPKKEGEGAPPGGSNSTASKQQATMLP 370
            :         ...:.:|.:....| :.|         ||...|.|      :||.|...::.:||
Mouse   375 TLQEQKERKFREKVRRPRSSSLLPCMCGMLHSRTMMLDGSYSESE------ANSLAGYPRSHILP 433

  Fly   371 LADEKIEKIEKIFDEMTKNRRIVTTTRRVVRPPLDADGPWIPRQESRIILTPTIAPPPPPPQPAA 435
                :.|:.:.|...:..|..:.::.::.:          :..|....|...|.|
Mouse   434 ----EEERPDNIVVHLALNSELTSSRKKGL----------LKGQMGLYIFQNTHA---------- 474

  Fly   436 PEPELPKPKLTPAQERLKRAIYIDRSSRVLFPALFASLNGIYWCVF 481
                                  ||:.||::|||.:...|.|||.||
Mouse   475 ----------------------IDKYSRLIFPAFYIVFNLIYWSVF 498

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ort	NP_524406.1	LIC	31..481	CDD:455710	137/491 (28%)
		LGIC_ECD_HisCl	51..235	CDD:349793	62/190 (33%)
		Cys-loop	155..169	CDD:349793	6/13 (46%)
Gabrr2	NP_001407795.1	LIC	74..498	CDD:455710	137/480 (29%)
		LGIC_ECD_GABAAR_rho	101..286	CDD:349806	62/189 (33%)
		Cys-loop	203..217	CDD:349806	6/13 (46%)