Protein Alignment ort and Gabrb2

DIOPT Version :10

• Sequence 1: NP_524406.1
• Gene: ort / 45910
• FlyBaseID: FBgn0003011
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: NP_001334243.1
• Gene: Gabrb2 / 14401
• MGIID: 95620
• Length: 512
• Species: Mus musculus
• Alignment Length: 542
• Identity: 147/542 - (27%)
• Similarity: 245/542 - (45%)
• Gaps: 109/542 - (20%)

  Fly     3 FQIIILVICTICMKHYAKGEFQQSL-------AITDILPEDIKRYDKMRPPKKEGQPTIVYFHVT 60
            |.:||..:|.            ||:       .:.:.:...:|.||....|...|.|..|..::.
Mouse    15 FPLIIAAVCA------------QSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNID 67

  Fly    61 VMGLDSIDENSMTYVADVFFAQTWKDHRLR---LPENMTQEYRLLEVDWLKNMWRPDSFFKNAKS 122
            :..:|.:.|.:|.|...::|.|.|:|.||.   :|.|:|.:.|:.:     .:|.||::|.|.|.
Mouse    68 IASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVAD-----QLWVPDTYFLNDKK 127

  Fly   123 VTFQTMTIPNHYMWLYKDKTILYMVKLTLKLSCIMNFAIYPHDTQECKLQMESLSHTTDDLIFQW 187
            .....:|:.|..:.|:.|.|:||.:::|...:|:|:...||.|.|.|.|::||..:||||:.|.|
Mouse   128 SFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYW 192

  Fly   188 DPTTPLVVDEN-------IELPQVALIRNETADCTQVYSTGNFTCLEVVFTLKRRLVYYVFNTYI 245
            ..      |:|       |||||.:::..:......|:|||::..|.:.|.|||.:.|::..||:
Mouse   193 RG------DDNAVTGVTKIELPQFSIVDYKLITKKVVFSTGSYPRLSLSFKLKRNIGYFILQTYM 251

  Fly   246 PTCMIVIMSWVSFWIKPEAAPARVTLGVTSLLTLSTQHAKSQSSLPPVSYLKAVDAFMSVCTVFV 310
            |:.:|.|:|||||||..:|:.|||.||:|::||::|.:...:.:||.:.|:||:|.::..|.|||
Mouse   252 PSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFV 316

  Fly   311 FMALMEYCLINIVLSDTPIPKPMAYPPKPVAGDGPKKEGEGAPPGGSNSTAS------------- 362
            ||||:||.|:|.:.                .|.||:::.:.|....:.:...
Mouse   317 FMALLEYALVNYIF----------------FGRGPQRQKKAAEKAANANNEKMRLDVNKMFYKDI 365

  Fly   363 KQQATML-----PLADEKIEKIEKIFD----EMTKNRRIVTTTRRVVRPPLDADG---------- 408
            ||..|..     |..|....:....:|    .|..:..|:.:|..:......::.
Mouse   366 KQNGTQYRSLWDPTGDLSPTRRTTNYDFSLYTMDPHENILLSTLEIKNEMATSEAVMGLGDPRST 430

  Fly   409 -------------PWIPRQE-SRIILTPTIAPPPPPPQPAAPEPELPKPKLTPAQERLKRAIYID 459
                         ..:||.. .|..|...:|......:..|.:.::..|.||....       ||
Mouse   431 MLAYDASSIQYRKAGLPRHSFGRNALERHVAQKKSRLRRRASQLKITIPDLTDVNA-------ID 488

  Fly   460 RSSRVLFPALFASLNGIYWCVF 481
            |.||:.||.:|:..|.:||..:
Mouse   489 RWSRIFFPVVFSFFNIVYWLYY 510

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ort	NP_524406.1	LIC	31..481	CDD:455710	141/505 (28%)
		LGIC_ECD_HisCl	51..235	CDD:349793	61/193 (32%)
		Cys-loop	155..169	CDD:349793	6/13 (46%)
Gabrb2	NP_001334243.1	LIC	9..510	CDD:455710	147/540 (27%)