Protein Alignment ort and Gabra6

DIOPT Version :9

• Sequence 1: NP_524406.1
• Gene: ort / 45910
• FlyBaseID: FBgn0003011
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: XP_036012221.1
• Gene: Gabra6 / 14399
• MGIID: 95618
• Length: 459
• Species: Mus musculus
• Alignment Length: 308
• Identity: 107/308 - (34%)
• Similarity: 160/308 - (51%)
• Gaps: 12/308 - (3%)

  Fly    20 KGEFQQSLAITDILPEDIKRYDKMRPPKKEGQPTIVYFHVTVMGLDSIDENSMTYVADVFFAQTW 84
            :|.| .|..::.||...::.||....|...|..|.|...:.|.....:.:..|.|..||||.|||
Mouse    24 EGNF-YSENVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTW 87

  Fly    85 KDHRLRL--PENMTQEYRLLEVDWLKNMWRPDSFFKNAKSVTFQTMTIPNHYMWLYKDKTILYMV 147
            .|.||:.  |..:.....|:    :..:|.||:||:|.|......||.||....|.::.||||.:
Mouse    88 TDERLKFKGPAEILSLNNLM----VSKIWTPDTFFRNGKKSIAHNMTTPNKLFRLMQNGTILYTM 148

  Fly   148 KLTLKLSCIMNFAIYPHDTQECKLQMESLSHTTDDLIFQWDPTTPL----VVDENIELPQVALIR 208
            :||:...|.|....:|.|...|.|:..|.::...::|:.| ...||    |.:|:..|.|..||.
Mouse   149 RLTINADCPMRLVNFPMDGHACPLKFGSYAYPKTEIIYTW-KKGPLYSVEVPEESSSLLQYDLIG 212

  Fly   209 NETADCTQVYSTGNFTCLEVVFTLKRRLVYYVFNTYIPTCMIVIMSWVSFWIKPEAAPARVTLGV 273
            ...:..|...:||.:..:.|.|.|:|::.|::...|.|..|.||:|.|||||..|:.|||...|:
Mouse   213 QTVSSETIKSNTGEYVIMTVYFHLQRKMGYFMIQIYTPCIMTVILSQVSFWINKESVPARTVFGI 277

  Fly   274 TSLLTLSTQHAKSQSSLPPVSYLKAVDAFMSVCTVFVFMALMEYCLIN 321
            |::||::|....::.|||.|||..|:|.|::||..|||.||:|:..:|
Mouse   278 TTVLTMTTLSISARHSLPKVSYATAMDWFIAVCFAFVFSALIEFAAVN 325

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ort	NP_524406.1	LIC	31..481	CDD:273305	104/297 (35%)
		Neur_chan_LBD	38..235	CDD:280998	62/202 (31%)
		Neur_chan_memb	243..>334	CDD:280999	38/79 (48%)
Gabra6	XP_036012221.1	LGIC_ECD_GABAAR_A6	42..239	CDD:349840	62/201 (31%)
		LGIC_TM_GABAAR_alpha	242..337	CDD:349854	39/84 (46%)
		TM1 helix	245..265	CDD:349854	10/19 (53%)
		TM2 helix	274..295	CDD:349854	6/20 (30%)
		TM3 helix	305..327	CDD:349854	10/21 (48%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810