Protein Alignment ort and Gabra4

DIOPT Version :10

• Sequence 1: NP_524406.1
• Gene: ort / 45910
• FlyBaseID: FBgn0003011
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: NP_001345970.1
• Gene: Gabra4 / 14397
• MGIID: 95616
• Length: 578
• Species: Mus musculus
• Alignment Length: 494
• Identity: 137/494 - (27%)
• Similarity: 215/494 - (43%)
• Gaps: 85/494 - (17%)

  Fly    50 GQPTIVYFHVTVMGLDSIDENSMTYVADVFFAQTWKDHRLRL--PENMTQEYRLLEVDWLKNM-- 110
            |..|.|...:.|.....:.:..|.|..||||.|||.|.||:.  |         :|:..|.||
Mouse    95 GPVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWIDKRLKYDGP---------IEILRLNNMMV 150

  Fly   111 ---WRPDSFFKNAKSVTFQTMTIPNHYMWLYKDKTILYMVKLTLKLSCIMNFAIYPHDTQECKLQ 172
               |.||:||:|.|......||.||....:.::.||||.::||:...|.|....:|.|...|.|:
Mouse   151 TKVWTPDTFFRNGKKSVSHNMTAPNKLFRIMRNGTILYTMRLTISAECPMRLVDFPMDGHACPLK 215

  Fly   173 MESLSHTTDDLIFQWDPTTPLVVD---ENIELPQVALIRNETADCTQVYSTGNFTCLEVVFTLKR 234
            ..|.::...::|:.|.......|:   |:..|.|..||....:..|....||.:..:.|.|.|:|
Mouse   216 FGSYAYPKSEMIYTWTKGPEKSVEVPKESSSLVQYDLIGQTVSSETIKSITGEYIVMTVYFHLRR 280

  Fly   235 RLVYYVFNTYIPTCMIVIMSWVSFWIKPEAAPARVTLGVTSLLTLSTQHAKSQSSLPPVSYLKAV 299
            ::.|::..||||..|.||:|.|||||..|:.|||...|:|::||::|....::.|||.|||..|:
Mouse   281 KMGYFMIQTYIPCIMTVILSQVSFWINKESVPARTVFGITTVLTMTTLSISARHSLPKVSYATAM 345

  Fly   300 DAFMSVCTVFVFMALMEYCLIN------IVLSDTPIPKPMAYPPK-PVAGDGPKKEGEGAPPGGS 357
            |.|::||..|||.||:|:..:|      :..:...|.||   ||: |.|....:|..|.:.....
Mouse   346 DWFIAVCFAFVFSALIEFAAVNYFTNIQMQKAKKKISKP---PPEVPAAPVLKEKHTETSLQNTH 407

  Fly   358 NSTASKQQATMLPLADEKIEKIEKIFDEMTKNRRIVTTTRRVVRPPLDADGPWIPRQESRIILTP 422
            .:...:::...|..::..::...::.:..:|...:..::....:..|.:.    |...||.....
Mouse   408 ANLNMRKRTNALVHSESDVKSRTEVGNHSSKTSAVQESSEATPKAHLASS----PNPFSRANAAE 468

  Fly   423 TI----------APPPP------------PPQP-----------------------AAPEPELPK 442
            |:          |.|.|            ..:|                       |.|.|..|.
Mouse   469 TMSAAARGLSSAASPSPHGTLRPASLGSASTRPAFGSRLGRIKTTVNTTGAAGNVSATPPPPAPP 533

  Fly   443 PKLTPAQERLKRAIYIDRSSRVLFPALFASLNGIYWCVF 481
            |..:...:       ||:.:|:|||..|.:.|.:||.|:
Mouse   534 PSGSGTSK-------IDKYARILFPVTFGAFNMVYWVVY 565

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ort	NP_524406.1	LIC	31..481	CDD:455710	136/492 (28%)
		LGIC_ECD_HisCl	51..235	CDD:349793	58/193 (30%)
		Cys-loop	155..169	CDD:349793	4/13 (31%)
Gabra4	NP_001345970.1	LIC	13..565	CDD:455710	136/492 (28%)
		LGIC_ECD_GABAAR_A4	57..281	CDD:349838	59/194 (30%)
		Cys-loop	198..212	CDD:349838	4/13 (31%)