Protein Alignment ort and Gabra3

DIOPT Version :10

• Sequence 1: NP_524406.1
• Gene: ort / 45910
• FlyBaseID: FBgn0003011
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: NP_001344745.1
• Gene: Gabra3 / 14396
• MGIID: 95615
• Length: 523
• Species: Mus musculus
• Alignment Length: 471
• Identity: 134/471 - (28%)
• Similarity: 213/471 - (45%)
• Gaps: 79/471 - (16%)

  Fly    30 TDILPEDIKRYDKMRPPKKEGQPTIVYFHVTVMGLDSIDENSMTYVADVFFAQTWKDHRLRLPEN 94
            |.||...:..||....|......|.|...:.|.....:.:..|.|..||||.|||.|.||:....
Mouse    99 TRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQTWHDERLKFDGP 163

  Fly    95 MTQEYRLLEVDWL--KNMWRPDSFFKNAKSVTFQTMTIPNHYMWLYKDKTILYMVKLTLKLSCIM 157
            |    ::|.::.|  ..:|.||:||.|.|......||.||..:.|..:.|:||.::||:...|.|
Mouse   164 M----KILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLLYTMRLTIHAECPM 224

  Fly   158 NFAIYPHDTQECKLQMESLSHTTDDLIFQWDPTTPLVVDENIELPQ----------------VAL 206
            :...:|.|...|.|:..|.::|..::|:.|    .|..::::|:.|                ..:
Mouse   225 HLEDFPMDVHACPLKFGSYAYTKAEVIYSW----TLGKNKSVEVAQDGSRLNQYDLLGHVVGTEI 285

  Fly   207 IRNETADCTQVYSTGNFTCLEVVFTLKRRLVYYVFNTYIPTCMIVIMSWVSFWIKPEAAPARVTL 271
            ||:         |||.:..:...|.|||::.|:|..||:|..|.||:|.||||:..|:.|||...
Mouse   286 IRS---------STGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVF 341

  Fly   272 GVTSLLTLSTQHAKSQSSLPPVSYLKAVDAFMSVCTVFVFMALMEYCLINIVLSDTPIPKPMAYP 336
            |||::||::|....:::|||.|:|..|:|.|::||..|||.||:|:..:|....     :..|:.
Mouse   342 GVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTK-----RSWAWE 401

  Fly   337 PKPVAGDGPKKEGEGAPPGGSNSTASKQQATMLPLADEKIEKIEKIFDEMTKNRRIVTTTRRVVR 401
            .|.|......|:...|.|...|:|.: ...|..|:             .:.|:....|.::....
Mouse   402 GKKVPEALEMKKKTPAAPTKKNTTFN-IVGTTYPI-------------NLAKDTEFSTISKSAAA 452

  Fly   402 PPLDADGPWIPRQESRIILTPTIAPPPPPPQPAAPEPELPKPKLTPAQERLKRAI-YIDRSSRVL 465
            |...:              |||          |...|:....:.:||:.:...:: .:|:.||::
Mouse   453 PSASS--------------TPT----------AIASPKATYVQDSPAETKTYNSVSKVDKISRII 493

  Fly   466 FPALFASLNGIYWCVF 481
            ||.|||..|.:||..:
Mouse   494 FPVLFAIFNLVYWATY 509

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ort	NP_524406.1	LIC	31..481	CDD:455710	133/468 (28%)
		LGIC_ECD_HisCl	51..235	CDD:349793	56/201 (28%)
		Cys-loop	155..169	CDD:349793	4/13 (31%)
Gabra3	NP_001344745.1	LIC	100..509	CDD:455710	133/468 (28%)
		LGIC_ECD_GABAAR_A3	106..305	CDD:349837	59/215 (27%)
		Cys-loop	222..236	CDD:349837	4/13 (31%)