Protein Alignment ort and Gabra4

DIOPT Version :9

• Sequence 1: NP_524406.1
• Gene: ort / 45910
• FlyBaseID: FBgn0003011
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: NP_542154.3
• Gene: Gabra4 / 140675
• RGDID: 621670
• Length: 552
• Species: Rattus norvegicus
• Alignment Length: 559
• Identity: 150/559 - (26%)
• Similarity: 234/559 - (41%)
• Gaps: 102/559 - (18%)

  Fly     2 VFQIIILVICT---------ICMKHYAKGEFQQSLAITDILPEDIKR--------YDKMRPPKKE 49
            |.::..:|:|:         :|:.........|:.....:.||:..|        ||....|...
  Rat     4 VQKVPAIVLCSGVSLALLHVLCLATCLNESPGQNSKDEKLCPENFTRILDSLLDGYDNRLRPGFG 68

  Fly    50 GQPTIVYFHVTVMGLDSIDENSMTYVADVFFAQTWKDHRLRL--PENMTQEYRLLEVDWLKNM-- 110
            |..|.|...:.|.....:.:..|.|..||||.|||.|.||:.  |         :|:..|.||
  Rat    69 GPVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWIDKRLKYDGP---------IEILRLNNMMV 124

  Fly   111 ---WRPDSFFKNAKSVTFQTMTIPNHYMWLYKDKTILYMVKLTLKLSCIMNFAIYPHDTQECKLQ 172
               |.||:||:|.|......||.||....:.::.||||.::||:...|.|....:|.|...|.|:
  Rat   125 TKVWTPDTFFRNGKKSVSHNMTAPNKLFRIMRNGTILYTMRLTISAECPMRLVDFPMDGHACPLK 189

  Fly   173 MESLSHTTDDLIFQWDPTTPLVVD---ENIELPQVALIRNETADCTQVYSTGNFTCLEVVFTLKR 234
            ..|.::...::|:.|.......|:   |:..|.|..||....:..|....||.:..:.|.|.|:|
  Rat   190 FGSYAYPKSEMIYTWTKGPEKSVEVPKESSSLVQYDLIGQTVSSETIKSITGEYIVMTVYFHLRR 254

  Fly   235 RLVYYVFNTYIPTCMIVIMSWVSFWIKPEAAPARVTLGVTSLLTLSTQHAKSQSSLPPVSYLKAV 299
            ::.|::..||||..|.||:|.|||||..|:.|||...|:|::||::|....::.|||.|||..|:
  Rat   255 KMGYFMIQTYIPCIMTVILSQVSFWINKESVPARTVFGITTVLTMTTLSISARHSLPKVSYATAM 319

  Fly   300 DAFMSVCTVFVFMALMEYCLIN------IVLSDTPIPKPMAYPPK-PVAGDGPKKEGEGAPPGGS 357
            |.|::||..|||.||:|:..:|      :..:...|.||   ||: |.|....:|..|.:.....
  Rat   320 DWFIAVCFAFVFSALIEFAAVNYFTNIQMQKAKKKISKP---PPEVPAAPVLKEKHTETSLQNTH 381

  Fly   358 NSTASKQQATMLPLADEKIEKIEKIFDEMTKNRRIVTTTRRVVRPPLDADGPWIPRQESRIILTP 422
            .:...:::...|..::..:....::.:..:|......::....:..|.:.    |...||.....
  Rat   382 ANLNMRKRTNALVHSESDVNSRTEVGNHSSKTTAAQESSETTPKAHLASS----PNPFSRANAAE 442

  Fly   423 TI----------APPPP----PPQP-------------------------------AAPEPELPK 442
            ||          |.|.|    .|.|                               |.|.|..|.
  Rat   443 TISAAARGLSSAASPSPHGTLQPAPLRSASARPAFGARLGRIKTTVNTTGVPGNVSATPPPSAPP 507

  Fly   443 PKLTPAQERLKRAIYIDRSSRVLFPALFASLNGIYWCVF 481
            |..:...:       ||:.:|:|||..|.:.|.:||.|:
  Rat   508 PSGSGTSK-------IDKYARILFPVTFGAFNMVYWVVY 539

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ort	NP_524406.1	LIC	31..481	CDD:273305	144/519 (28%)
		Neur_chan_LBD	38..235	CDD:280998	63/214 (29%)
		Neur_chan_memb	243..>334	CDD:280999	43/96 (45%)
Gabra4	NP_542154.3	LIC	13..539	CDD:273305	147/548 (27%)
		Neur_chan_LBD	49..256	CDD:280998	64/215 (30%)
		Neur_chan_memb	263..536	CDD:280999	75/286 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	353..436		13/89 (15%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	448..470		5/21 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	486..513		5/26 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810