Protein Alignment ort and Gabrg1

DIOPT Version :10

• Sequence 1: NP_524406.1
• Gene: ort / 45910
• FlyBaseID: FBgn0003011
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: NP_542153.1
• Gene: Gabrg1 / 140674
• RGDID: 621732
• Length: 465
• Species: Rattus norvegicus
• Alignment Length: 470
• Identity: 136/470 - (28%)
• Similarity: 213/470 - (45%)
• Gaps: 81/470 - (17%)

  Fly    29 ITDILPEDIKRYDKMRPPKKEGQPTIVYFHVTVMGLDSIDENSMTYVADVFFAQTWKDHRLRLPE 93
            ||.||...::.||....|....:||::...|.|..:..:|..:|.|..|:.|||||.|.||:.
  Rat    64 ITQILNSLLQGYDNKLRPDIGVRPTVIETDVYVNSIGPVDPINMEYTIDIIFAQTWFDSRLKF-- 126

  Fly    94 NMTQEYRLLEVDWLKNMWRPDSFFKNAKSVTFQTMTIPNHYMWLYKDKTILYMVKLTLKLSCIMN 158
            |.|.:..:|..:.:..:|.||:||:|::......:|.||..:.::.|..:||.::||:...|.:.
  Rat   127 NSTMKVLMLNSNMVGKIWIPDTFFRNSRKSDAHWITTPNRLLRIWSDGRVLYTLRLTINAECYLQ 191

  Fly   159 FAIYPHDTQECKLQMESLSHTTDDLIFQWDPTTPLVVDENI-ELPQVALI--RNETADCTQVYST 220
            ...:|.|...|.|:..|..:..:::.::|...:..|.|... .|.|.|.:  ||.|.....:  :
  Rat   192 LHNFPMDEHSCPLEFSSYGYPKNEIEYKWKKPSVEVADPKYWRLYQFAFVGLRNSTEISHTI--S 254

  Fly   221 GNFTCLEVVFTLKRRLVYYVFNTYIPTCMIVIMSWVSFWIKPEAAPARVTLGVTSLLTLSTQHAK 285
            |::..:.:.|.|.||:.|:...||||..:.|::|||||||..:|.|||.:||:|::||::|....
  Rat   255 GDYIIMTIFFDLSRRMGYFTIQTYIPCILTVVLSWVSFWINKDAVPARTSLGITTVLTMTTLSTI 319

  Fly   286 SQSSLPPVSYLKAVDAFMSVCTVFVFMALMEYCLINIVLSDTPIPKPMAYPPKPVAGDGPKKEGE 350
            ::.|||.|||:.|:|.|:|||.:|||.|||||..::...|:.         ......|...|...
  Rat   320 ARKSLPKVSYVTAMDLFVSVCFIFVFAALMEYGTLHYFTSNN---------KGKTTRDRKLKSKT 375

  Fly   351 GAPPG---GSNSTASKQQATMLPLADEKIEKIEKIFDEMTKNRRIVTT-------TRRVVRPPLD 405
            ...||   ||         |::|:.:..:.:.|..:.......:...|       .|
  Rat   376 SVSPGLHAGS---------TLIPMNNISMPQGEDDYGYQCLEGKDCATFFCCFEDCR-------- 423

  Fly   406 ADGPWIPRQESRIILTPTIAPPPPPPQPAAPEPELPKPKLTPAQERLKRAIYIDRSSRVLFPALF 470
             .|.|   :|.||.:                                 |...||..||:.||..|
  Rat   424 -TGSW---REGRIHI---------------------------------RIAKIDSYSRIFFPTAF 451

  Fly   471 ASLNGIYWCVFYEYL 485
            |..|.:|| |.|.||
  Rat   452 ALFNLVYW-VGYLYL 465

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ort	NP_524406.1	LIC	31..481	CDD:455710	130/462 (28%)
		LGIC_ECD_HisCl	51..235	CDD:349793	51/186 (27%)
		Cys-loop	155..169	CDD:349793	3/13 (23%)
Gabrg1	NP_542153.1	LIC	66..462	CDD:455710	131/463 (28%)
		LGIC_ECD_GABAAR_G	88..269	CDD:349801	50/184 (27%)
		Cys-loop	188..202	CDD:349801	3/13 (23%)